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dc.contributor.authorColson, Natalieen_US
dc.contributor.authorFernandez, Francescaen_US
dc.contributor.authorGriffiths, Lynen_US
dc.date.accessioned2017-04-24T08:41:20Z
dc.date.available2017-04-24T08:41:20Z
dc.date.issued2007en_US
dc.date.modified2009-01-23T05:38:00Z
dc.identifier.issn02724391en_US
dc.identifier.doi10.1002/ddr.20192en_AU
dc.identifier.urihttp://hdl.handle.net/10072/18986
dc.description.abstractMigraine is a common complex neurological disorder with a well-known but poorly characterized genetic liability. The search for migraine susceptibility genes has been the focus of intense research. It is now believed that common migraine is not a single gene disorder, but attributable to several potentially interacting genetic variants. These variants may differ in each sufferer and interact with environmental factors to set the individual migraine threshold. This genetic liability may play an important role in the clinical heterogeneity seen in migraine and also in the variability of treatment response. This review will look at genetic loci implicated in migraine to date and consider their current or prospective role in migraine therapy. To elucidate the complex nature of migraine genetic liability, approaches that consider detailed endophenotypic profiles that encompass treatment response may provide much more relevant information than simple end diagnosisen_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherJohn Wiley & Sons, Inc.en_US
dc.publisher.placeUnited Statesen_US
dc.publisher.urihttp://www3.interscience.wiley.com/cgi-bin/jhome/34597en_AU
dc.relation.ispartofstudentpublicationNen_AU
dc.relation.ispartofpagefrom282en_US
dc.relation.ispartofpageto293en_US
dc.relation.ispartofjournalDrug Development Researchen_US
dc.relation.ispartofvolume68en_US
dc.rights.retentionYen_AU
dc.subject.fieldofresearchcode270210en_US
dc.titleMigraine genetics and prospects for pharmacotherapyen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.facultyGriffith Health, School of Medical Scienceen_US
gro.rights.copyrightCopyright 2007 John Wiley & Sons, Ltd. Self-archiving of the author-manuscript version is not yet supported by this publisher. Please refer to the journal link for access to the definitive, published version or contact the author for more information.en_AU
gro.date.issued2007
gro.hasfulltextNo Full Text


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    Contains articles published by Griffith authors in scholarly journals.

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