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dc.contributor.authorAl-Hashimi, Ibtisamen_US
dc.contributor.authorSchifter, Marken_US
dc.contributor.authorB. Lockhart, Peteren_US
dc.contributor.authorWray, Daviden_US
dc.contributor.authorBrennan, Michaelen_US
dc.contributor.authorA. Migliorati, Cesaren_US
dc.contributor.authorAxell, Tonyen_US
dc.contributor.authorJ. Bruce, Alisonen_US
dc.contributor.authorCarpenter, Williamen_US
dc.contributor.authorEisenberg, Ellenen_US
dc.contributor.authorB. Epstein, Joelen_US
dc.contributor.authorHolmstrup, Palleen_US
dc.contributor.authorJontell, Matsen_US
dc.contributor.authorLozada-Nur, Francinaen_US
dc.contributor.authorNair, Rajen_US
dc.contributor.authorSilverman, Buden_US
dc.contributor.authorThongprasom, Kobkanen_US
dc.contributor.authorThornhill, Martinen_US
dc.contributor.authorWarnakulasuriya, Samanen_US
dc.contributor.authorvan der Waal, Isaacen_US
dc.description.abstractSeveral therapeutic agents have been investigated for the treatment of oral lichen planus (OLP). Among these are corticosteroids, retinoids, cyclosporine, and phototherapy, in addition to other treatment modalities. A systematic review of clinical trials showed that particularly topical corticosteroids are often effective in the management of symptomatic OLP lichen planus. Systemic corticosteroids should be only considered for severe widespread OLP and for lichen planus involving other mucocutaneous sites. Because of the ongoing controversy in the literature about the possible premalignant character of OLP, periodic follow-up is recommended. There is a spectrum of oral lichen planus-like ("lichenoid") lesions that may confuse the differential diagnosis. These include lichenoid contact lesions, lichenoid drug reactions and lichenoid lesions of graft-versus-host disease. In regard to the approach to oral lichenoid contact lesions the value of patch testing remains controversial. Confirmation of the diagnosis of an oral lichenoid drug reaction may be difficult, since empiric withdrawal of the suspected drug and/or its substitution by an alternative agent may be complicated. Oral lichenoid lesions of graft-versus-host disease (OLL-GVHD) are recognized to have an association with malignancy. Local therapy for these lesions rests in topical agents, predominantly corticosteroids.en_US
dc.publisherMosby, Inc.en_US
dc.publisher.placeUnited Statesen_US
dc.relation.ispartofeditionSuppliment 1en_US
dc.relation.ispartofjournalOral surgery, oral medicine, oral pathology, oral radiology and endodontologyen_US
dc.titleOral lichen planus and oral lichenoid lesions: diagnostic and therapeutic considerationsen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.hasfulltextNo Full Text

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