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dc.contributor.authorDu, Lipingen_US
dc.contributor.authorWu, Shuanhuen_US
dc.contributor.authorLiew, Alan Wee-Chungen_US
dc.contributor.authorK. Smith, Daviden_US
dc.contributor.authorYan, Hongen_US
dc.date.accessioned2017-05-03T15:20:44Z
dc.date.available2017-05-03T15:20:44Z
dc.date.issued2008en_US
dc.date.modified2011-11-18T06:03:32Z
dc.identifier.issn17445485en_US
dc.identifier.doi10.1504/IJBRA.2008.019579en_AU
dc.identifier.urihttp://hdl.handle.net/10072/20270
dc.description.abstractWe propose a new strategy to analyze the periodicity of gene expression profiles using Singular Spectrum Analysis (SSA) and Autoregressive (AR) model based spectral estimation. By combining the advantages of SSA and AR modeling, more periodic genes are extracted in the Plasmodium falciparum data set, compared with the classical Fourier analysis technique. We are able to identify more gene targets for new drug discovery, and by checking against the seven well-known malaria vaccine candidates, we have found five additional genes that warrant further biological verification.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.format.extent139636 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherInderscienceen_US
dc.publisher.placeUnited Statesen_US
dc.relation.ispartofstudentpublicationNen_AU
dc.relation.ispartofpagefrom337en_US
dc.relation.ispartofpageto349en_US
dc.relation.ispartofissue3en_US
dc.relation.ispartofjournalInternational Journal of Bioinformatics Research and Applicationsen_US
dc.relation.ispartofvolume4en_US
dc.rights.retentionYen_AU
dc.subject.fieldofresearchcode280204en_US
dc.subject.fieldofresearchcode270201en_US
dc.titleSpectral analysis of microarray gene expression time series data of Plasmodium falciparumen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.rights.copyrightCopyright 2008 Inderscience Publishers. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal website for access to the definitive, published version.en_AU
gro.date.issued2008
gro.hasfulltextFull Text


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