• myGriffith
    • Staff portal
    • Contact Us⌄
      • Future student enquiries 1800 677 728
      • Current student enquiries 1800 154 055
      • International enquiries +61 7 3735 6425
      • General enquiries 07 3735 7111
      • Online enquiries
      • Staff phonebook
    View Item 
    •   Home
    • Griffith Research Online
    • Journal articles
    • View Item
    • Home
    • Griffith Research Online
    • Journal articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

  • All of Griffith Research Online
    • Communities & Collections
    • Authors
    • By Issue Date
    • Titles
  • This Collection
    • Authors
    • By Issue Date
    • Titles
  • Statistics

  • Most Popular Items
  • Statistics by Country
  • Most Popular Authors
  • Support

  • Contact us
  • FAQs
  • Admin login

  • Login
  • Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs

    Author(s)
    Okazaki, Y.
    Furuno, M.
    Kasukawa, T.
    Adachi, J.
    Bono, H.
    Kondo, S.
    Nikaido, I.
    Osato, N.
    Saito, R.
    Suzuki, H.
    Yamanaka, I.
    Kiyosawa, H.
    Yagi, K.
    Tomaru, Y.
    Hasegawa, Y.
    Nogami, A.
    Schonbach, C.
    Gojobori, T.
    Baldarelli, R.
    Hill, D. P.
    Bult, C.
    Hume, D. A.
    Quackenbush, J.
    Schrimi, L. M.
    Kanapin, A.
    Matsuda, H.
    Batalov, S.
    Beisel, K. W.
    Blake, J. A.
    Bradt, D.
    Brusic, V.
    Chothia, C.
    Corbani, L. E.
    Cousins, S.
    Dalla, E.
    Dragani, T.A.
    Fletcher, C. F.
    Forrest, Alistair Raymond Russell
    Frazer, K. S.
    Gaasterland, T.
    Gariboldi, M.
    Gissi, C.
    Godzik, A.
    Gough, J.
    Grimmond, S.
    Gustincich, S.
    Hirokawa, N.
    Jackson, I. J.
    Jarvis, E. D.
    Kanai, A.
    Kawaji, H.
    Kawasawa, Y.
    Kedzierski, R. M.
    King, B. L.
    Konagaya, A.
    Kurochkin, I. V.
    Lee, Y.
    Lenhard, B.
    Lyons, P. A.
    Maglott, D. R.
    Maltais, L.
    Marchionni, L.
    McKenzie, L.
    Miki, H.
    Nagashima, T.
    Numata, K.
    Okido, T.
    Pavan, W. J.
    Pertea, G.
    Pesole, G.
    Petrovsky, N.
    Pillai, R.
    Pontius, J. U.
    Qi, D.
    Ramachandran, S.
    Ravasi, T.
    Reed, J. C.
    Reed, D. J.
    Reid, J.
    Ring, B. Z.
    Ringwald, M.
    Sandelin, A .
    Schneider, C.
    Semple, C. A. M.
    Setou, M.
    Shimada, K.
    Sultana, R.
    Takenaka, Y.
    Taylor, M. S.
    Teasdale, R. D.
    Tomita, M.
    Verardo, R.
    Wagner, L.
    Wahlestedt, C.
    Wang, Y.
    Watanabe, Y.
    Wells, C.
    Wilming, L. G.
    al, et
    Griffith University Author(s)
    Wells, Christine
    Year published
    2002
    Metadata
    Show full item record
    Abstract
    Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There is an international collaborative effort to identify all full-length mRNA transcripts from the mouse, and to ensure that each is represented in a physical collection of clones. Here we report the manual annotation of 60,770 full-length mouse complementary DNA sequences. These are clustered into 33,409 'transcriptional units', contributing 90.1% of a newly established mouse transcriptome database. Of these transcriptional units, 4,258 are new protein-coding and 11,665 are new non-coding messages, indicating that non-coding ...
    View more >
    Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There is an international collaborative effort to identify all full-length mRNA transcripts from the mouse, and to ensure that each is represented in a physical collection of clones. Here we report the manual annotation of 60,770 full-length mouse complementary DNA sequences. These are clustered into 33,409 'transcriptional units', contributing 90.1% of a newly established mouse transcriptome database. Of these transcriptional units, 4,258 are new protein-coding and 11,665 are new non-coding messages, indicating that non-coding RNA is a major component of the transcriptome. 41% of all transcriptional units showed evidence of alternative splicing. In protein-coding transcripts, 79% of splice variations altered the protein product. Whole-transcriptome analyses resulted in the identification of 2,431 sense–antisense pairs. The present work, completely supported by physical clones, provides the most comprehensive survey of a mammalian transcriptome so far, and is a valuable resource for functional genomics.
    View less >
    Journal Title
    Nature
    Volume
    420
    Issue
    6915
    Publisher URI
    http://www.nature.com/nature/index.html
    DOI
    https://doi.org/10.1038/nature01266
    Subject
    Biochemistry and Cell Biology
    Publication URI
    http://hdl.handle.net/10072/20587.1
    Collection
    • Journal articles

    Footer

    Disclaimer

    • Privacy policy
    • Copyright matters
    • CRICOS Provider - 00233E

    Tagline

    • Gold Coast
    • Logan
    • Brisbane - Queensland, Australia
    First Peoples of Australia
    • Aboriginal
    • Torres Strait Islander