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dc.contributor.authorOkazaki, Y.en_AU
dc.contributor.authorFuruno, M.en_AU
dc.contributor.authorKasukawa, T.en_AU
dc.contributor.authorAdachi, J.en_AU
dc.contributor.authorBono, H.en_AU
dc.contributor.authorKondo, S.en_AU
dc.contributor.authorNikaido, I.en_AU
dc.contributor.authorOsato, N.en_AU
dc.contributor.authorSaito, R.en_AU
dc.contributor.authorSuzuki, H.en_AU
dc.contributor.authorYamanaka, I.en_AU
dc.contributor.authorKiyosawa, H.en_AU
dc.contributor.authorYagi, K.en_AU
dc.contributor.authorTomaru, Y.en_AU
dc.contributor.authorHasegawa, Y.en_AU
dc.contributor.authorNogami, A.en_AU
dc.contributor.authorSchonbach, C.en_AU
dc.contributor.authorGojobori, T.en_AU
dc.contributor.authorBaldarelli, R.en_AU
dc.contributor.authorHill, D. P.en_AU
dc.contributor.authorBult, C.en_AU
dc.contributor.authorHume, D. A.en_AU
dc.contributor.authorQuackenbush, J.en_AU
dc.contributor.authorSchrimi, L. M.en_AU
dc.contributor.authorKanapin, A.en_AU
dc.contributor.authorMatsuda, H.en_AU
dc.contributor.authorBatalov, S.en_AU
dc.contributor.authorBeisel, K. W.en_AU
dc.contributor.authorBlake, J. A.en_AU
dc.contributor.authorBradt, D.en_AU
dc.contributor.authorBrusic, V.en_AU
dc.contributor.authorChothia, C.en_AU
dc.contributor.authorCorbani, L. E.en_AU
dc.contributor.authorCousins, S.en_AU
dc.contributor.authorDalla, E.en_AU
dc.contributor.authorDragani, T.A.en_AU
dc.contributor.authorFletcher, C. F.en_AU
dc.contributor.authorForrest, Alistair Raymond Russellen_AU
dc.contributor.authorFrazer, K. S.en_AU
dc.contributor.authorGaasterland, T.en_AU
dc.contributor.authorGariboldi, M.en_AU
dc.contributor.authorGissi, C.en_AU
dc.contributor.authorGodzik, A.en_AU
dc.contributor.authorGough, J.en_AU
dc.contributor.authorGrimmond, S.en_AU
dc.contributor.authorGustincich, S.en_AU
dc.contributor.authorHirokawa, N.en_AU
dc.contributor.authorJackson, I. J.en_AU
dc.contributor.authorJarvis, E. D.en_AU
dc.contributor.authorKanai, A.en_AU
dc.contributor.authorKawaji, H.en_AU
dc.contributor.authorKawasawa, Y.en_AU
dc.contributor.authorKedzierski, R. M.en_AU
dc.contributor.authorKing, B. L.en_AU
dc.contributor.authorKonagaya, A.en_AU
dc.contributor.authorKurochkin, I. V.en_AU
dc.contributor.authorLee, Y.en_AU
dc.contributor.authorLenhard, B.en_AU
dc.contributor.authorLyons, P. A.en_AU
dc.contributor.authorMaglott, D. R.en_AU
dc.contributor.authorMaltais, L.en_AU
dc.contributor.authorMarchionni, L.en_AU
dc.contributor.authorMcKenzie, L.en_AU
dc.contributor.authorMiki, H.en_AU
dc.contributor.authorNagashima, T.en_AU
dc.contributor.authorNumata, K.en_AU
dc.contributor.authorOkido, T.en_AU
dc.contributor.authorPavan, W. J.en_AU
dc.contributor.authorPertea, G.en_AU
dc.contributor.authorPesole, G.en_AU
dc.contributor.authorPetrovsky, N.en_AU
dc.contributor.authorPillai, R.en_AU
dc.contributor.authorPontius, J. U.en_AU
dc.contributor.authorQi, D.en_AU
dc.contributor.authorRamachandran, S.en_AU
dc.contributor.authorRavasi, T.en_AU
dc.contributor.authorReed, J. C.en_AU
dc.contributor.authorReed, D. J.en_AU
dc.contributor.authorReid, J.en_AU
dc.contributor.authorRing, B. Z.en_AU
dc.contributor.authorRingwald, M.en_AU
dc.contributor.authorSandelin, A .en_AU
dc.contributor.authorSchneider, C.en_AU
dc.contributor.authorSemple, C. A. M.en_AU
dc.contributor.authorSetou, M.en_AU
dc.contributor.authorShimada, K.en_AU
dc.contributor.authorSultana, R.en_AU
dc.contributor.authorTakenaka, Y.en_AU
dc.contributor.authorTaylor, M. S.en_AU
dc.contributor.authorTeasdale, R. D.en_AU
dc.contributor.authorTomita, M.en_AU
dc.contributor.authorVerardo, R.en_AU
dc.contributor.authorWagner, L.en_AU
dc.contributor.authorWahlestedt, C.en_AU
dc.contributor.authorWang, Y.en_AU
dc.contributor.authorWatanabe, Y.en_AU
dc.contributor.authorWells, C.en_AU
dc.contributor.authorWilming, L. G.en_AU
dc.contributor.authoral, eten_AU
dc.date.accessioned2007-12-05en_AU
dc.date.accessioned2017-03-01T20:17:30Z
dc.date.available2017-03-01T20:17:30Z
dc.date.issued2002en_AU
dc.date.modified2008-11-26T04:13:08Z
dc.identifier.issn0028-0836en_AU
dc.identifier.doihttp://dx.doi.org/10.1038/nature01266en_AU
dc.identifier.urihttp://hdl.handle.net/10072/20587.1
dc.description.abstractOnly a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There is an international collaborative effort to identify all full-length mRNA transcripts from the mouse, and to ensure that each is represented in a physical collection of clones. Here we report the manual annotation of 60,770 full-length mouse complementary DNA sequences. These are clustered into 33,409 'transcriptional units', contributing 90.1% of a newly established mouse transcriptome database. Of these transcriptional units, 4,258 are new protein-coding and 11,665 are new non-coding messages, indicating that non-coding RNA is a major component of the transcriptome. 41% of all transcriptional units showed evidence of alternative splicing. In protein-coding transcripts, 79% of splice variations altered the protein product. Whole-transcriptome analyses resulted in the identification of 2,431 sense–antisense pairs. The present work, completely supported by physical clones, provides the most comprehensive survey of a mammalian transcriptome so far, and is a valuable resource for functional genomics.en_AU
dc.description.peerreviewedYesen_AU
dc.description.publicationstatusYesen_AU
dc.language.isoen_AU
dc.publisherNature Publishing Groupen_AU
dc.publisher.placeUnited Kingdomen_AU
dc.publisher.urihttp://www.nature.com/nature/index.htmlen_AU
dc.relation.ispartofpagefrom563en_AU
dc.relation.ispartofpageto573en_AU
dc.relation.ispartofissue6915en_AU
dc.relation.ispartofjournalNatureen_AU
dc.relation.ispartofvolume420en_AU
dc.subject.fieldofresearchBiochemistry and Cell Biologyen_AU
dc.subject.fieldofresearchcode270199en_AU
dc.titleAnalysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAsen_AU
dc.type.descriptionJournal Articles (Refereed Article)en_AU
dc.type.codec1xen_AU
gro.facultyEskitis, Inst Cell&Molecular Therapiesen_AU
gro.date.issued2002
gro.hasfulltextNo Full Text


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