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dc.contributor.authorPihlstrom, BL
dc.contributor.authorMichalowicz, BS
dc.contributor.authorJohnson, NW
dc.contributor.editorDr. Richard Horton
dc.date.accessioned2017-05-03T15:03:33Z
dc.date.available2017-05-03T15:03:33Z
dc.date.issued2005
dc.date.modified2009-01-16T06:22:40Z
dc.identifier.issn0140-6736
dc.identifier.doi10.1016/S0140-6736(05)67728-8
dc.identifier.urihttp://hdl.handle.net/10072/21062
dc.description.abstractThe periodontal diseases are highly prevalent and can affect up to 90% of the worldwide population. Gingivitis, the mildest form of periodontal disease, is caused by the bacterial biofilm (dental plaque) that accumulates on teeth adjacent to the gingiva (gums). However, gingivitis does not affect the underlying supporting structures of the teeth and is reversible. Periodontitis results in loss of connective tissue and bone support and is a major cause of tooth loss in adults. In addition to pathogenic microorganisms in the biofilm, genetic and environmental factors, especially tobacco use, contribute to the cause of these diseases. Genetic, dermatological, haematological, granulomatous, immunosuppressive, and neoplastic disorders can also have periodontal manifestations. Common forms of periodontal disease have been associated with adverse pregnancy outcomes, cardiovascular disease, stroke, pulmonary disease, and diabetes, but the causal relations have not been established. Prevention and treatment are aimed at controlling the bacterial biofilm and other risk factors, arresting progressive disease, and restoring lost tooth support.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherThe Lancet Publishing Group
dc.publisher.placeUnited Kingdom
dc.publisher.urihttp://www.elsevier.com/wps/find/journaldescription.cws_home/31066/description#description
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom1809
dc.relation.ispartofpageto1820
dc.relation.ispartofissue9499
dc.relation.ispartofjournalLancet
dc.relation.ispartofvolume366
dc.rights.retentionY
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchcode32
dc.titlePeriodontal diseases
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2005
gro.hasfulltextNo Full Text
gro.griffith.authorJohnson, Newell W.


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