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dc.contributor.authorBrown, CL
dc.contributor.authorWhitehouse, MW
dc.contributor.authorTiekink, ERT
dc.contributor.authorBushell, GR
dc.date.accessioned2017-05-03T11:28:13Z
dc.date.available2017-05-03T11:28:13Z
dc.date.issued2008
dc.date.modified2011-06-13T22:57:56Z
dc.identifier.issn0925-4692
dc.identifier.doi10.1007/s10787-007-0017-6
dc.identifier.urihttp://hdl.handle.net/10072/21294
dc.description.abstractMetallic gold (Au੠is a likely biotransformation product of monovalent gold, Au(I) whenever it is dissociated from in vivo ligands, Auࠢeing formed either by bioreduction or by spontaneous dismutation (with co-production of trivalent gold). This review discusses the preparation and some biologically relevant properties of colloidal metallic gold (CMG) in its nano-particulate form. Tyndall's purple, a well characterised preparation of CMG, shows potent anti-arthritic activity in rats, approximately 103 times that of sodium aurothiomalate (Myocrysin). Even more remarkable is its broader spectrum of action in rats compared to this classic DMARD.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherBirkhauser Verlag
dc.publisher.placeSwitzerland
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom133
dc.relation.ispartofpageto137
dc.relation.ispartofjournalInflammopharmacology
dc.relation.ispartofvolume16
dc.rights.retentionY
dc.subject.fieldofresearchPharmacology and pharmaceutical sciences
dc.subject.fieldofresearchcode3214
dc.titleColloidal metallic gold is not bio-inert
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2008
gro.hasfulltextNo Full Text
gro.griffith.authorBushell, Gillian R.


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