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dc.contributor.authorCock, Ian
dc.date.accessioned2017-05-03T11:28:57Z
dc.date.available2017-05-03T11:28:57Z
dc.date.issued2008
dc.identifier.issn19378289
dc.identifier.urihttp://hdl.handle.net/10072/21381
dc.description.abstractMethanolic extracts of Aloe barbadensis Miller inner leaf gel were fractionated by RP-HPLC and the resultant fractions were tested for inhibitory activity against a panel of bacteria and fungi. Five fractions were identified as having antimicrobial activity. Fraction 1 had the broadest antibacterial activity, being capable of inhibiting growth of both Gram-positive and Gram-negative bacteria as well as inhibiting growth of a nystatin resistant strain of the fungus Aspergillus niger. Fraction 1 had similar UV spectral properties as aloe emodin and was chromatographically identical to the pure compound. The other fractions tested were much more selective in their antimicrobial activities, being only capable of inhibiting the growth of specific Gram-negative rod bacteria. Two of these antimicrobial fractions were identified by ESI mass spectroscopy as being isomers of 8-C-߭D-[2-0-(E)-coumaroyl] glucopyranosyl -2-[2-hydroxy]-propyl-7-methoxy-5-methylchromone.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent167018 bytes
dc.format.extent27695 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.languageEnglish
dc.language.isoeng
dc.publisherInternet Scientific Publications LLC
dc.publisher.placeUnited States
dc.publisher.urihttp://ispub.com/IJMB/4/2/8590
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom1
dc.relation.ispartofpageto11
dc.relation.ispartofissue2
dc.relation.ispartofjournalThe Internet Journal of Microbiology
dc.relation.ispartofvolume4
dc.rights.retentionY
dc.subject.fieldofresearchMicrobiology
dc.subject.fieldofresearchMedical Microbiology
dc.subject.fieldofresearchcode0605
dc.subject.fieldofresearchcode1108
dc.titleAntimicrobial Activity of Aloe barbadensis Miller Leaf Gel Components
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Sciences, School of Natural Sciences
gro.rights.copyright© 2008 Internet Scientific Publications.This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
gro.date.issued2015-08-04T00:17:48Z
gro.hasfulltextFull Text
gro.griffith.authorCock, Ian E.


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