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dc.contributor.authorCock, Ianen_US
dc.date.accessioned2017-05-03T11:28:57Z
dc.date.available2017-05-03T11:28:57Z
dc.date.issued2008en_US
dc.identifier.issn19378289en_US
dc.identifier.urihttp://hdl.handle.net/10072/21381
dc.description.abstractMethanolic extracts of Aloe barbadensis Miller inner leaf gel were fractionated by RP-HPLC and the resultant fractions were tested for inhibitory activity against a panel of bacteria and fungi. Five fractions were identified as having antimicrobial activity. Fraction 1 had the broadest antibacterial activity, being capable of inhibiting growth of both Gram-positive and Gram-negative bacteria as well as inhibiting growth of a nystatin resistant strain of the fungus Aspergillus niger. Fraction 1 had similar UV spectral properties as aloe emodin and was chromatographically identical to the pure compound. The other fractions tested were much more selective in their antimicrobial activities, being only capable of inhibiting the growth of specific Gram-negative rod bacteria. Two of these antimicrobial fractions were identified by ESI mass spectroscopy as being isomers of 8-C-߭D-[2-0-(E)-coumaroyl] glucopyranosyl -2-[2-hydroxy]-propyl-7-methoxy-5-methylchromone.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_US
dc.format.extent167018 bytes
dc.format.extent27695 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.languageEnglishen_US
dc.language.isoen_US
dc.publisherInternet Scientific Publications LLCen_US
dc.publisher.placeUnited Statesen_US
dc.publisher.urihttp://ispub.com/IJMB/4/2/8590en_US
dc.relation.ispartofstudentpublicationNen_US
dc.relation.ispartofpagefrom1en_US
dc.relation.ispartofpageto11en_US
dc.relation.ispartofissue2en_US
dc.relation.ispartofjournalThe Internet Journal of Microbiologyen_US
dc.relation.ispartofvolume4en_US
dc.rights.retentionYen_US
dc.subject.fieldofresearchcode270301en_US
dc.titleAntimicrobial Activity of Aloe barbadensis Miller Leaf Gel Componentsen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.facultyGriffith Sciences, School of Natural Sciencesen_US
gro.rights.copyrightCopyright 2008 Internet Scientific Publications.This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.en_US
gro.date.issued2015-08-04T00:17:48Z
gro.hasfulltextFull Text


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