• myGriffith
    • Staff portal
    • Contact Us⌄
      • Future student enquiries 1800 677 728
      • Current student enquiries 1800 154 055
      • International enquiries +61 7 3735 6425
      • General enquiries 07 3735 7111
      • Online enquiries
      • Staff phonebook
    View Item 
    •   Home
    • Griffith Research Online
    • Journal articles
    • View Item
    • Home
    • Griffith Research Online
    • Journal articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

  • All of Griffith Research Online
    • Communities & Collections
    • Authors
    • By Issue Date
    • Titles
  • This Collection
    • Authors
    • By Issue Date
    • Titles
  • Statistics

  • Most Popular Items
  • Statistics by Country
  • Most Popular Authors
  • Support

  • Contact us
  • FAQs
  • Admin login

  • Login
  • Well-differentiated thyroid carcinoma in Hong Kong Chinese patients under 21 years of age: a 35-year experience

    Author(s)
    Lee, YM
    Lo, CY
    Lam, KY
    Wan, KY
    Tam, PKH
    Griffith University Author(s)
    Lam, Alfred K.
    Year published
    2002
    Metadata
    Show full item record
    Abstract
    Sporadic well-differentiated thyroid cancer is an uncommon condition in children, adolescents, and young adults. It is associated with distinct clinicopathologic features and prognosis. The present study reviews our experience in management of this condition in ethnic Chinese in Hong Kong. Study Design: A retrospective study was performed to review the clinicopathologic features and outcomes of 34 patients less than 21 years of age with well-differentiated thyroid carcinoma over a 35-year period. Median followup was 15.2 years (range 1 to 32.5 years). Results: There were 27 girls and 7 boys with a median age of 19 years ...
    View more >
    Sporadic well-differentiated thyroid cancer is an uncommon condition in children, adolescents, and young adults. It is associated with distinct clinicopathologic features and prognosis. The present study reviews our experience in management of this condition in ethnic Chinese in Hong Kong. Study Design: A retrospective study was performed to review the clinicopathologic features and outcomes of 34 patients less than 21 years of age with well-differentiated thyroid carcinoma over a 35-year period. Median followup was 15.2 years (range 1 to 32.5 years). Results: There were 27 girls and 7 boys with a median age of 19 years (range 10 to 21 years). None had previous history of irradiation. Twenty-eight patients had papillary and six had follicular carcinomas. Operative procedures included total thyroidectomy (n = 27) and unilateral lobectomy (n = 7) with concomitant neck dissection performed in nine patients. The median tumor size was 2 cm and extrathyroidal invasion was present in 19 tumors. Adjuvant radioactive iodine treatment was administered to 18 patients after total thyroidectomy. Disease progression or recurrence rate was 24% and 27% at 5 and 10 years, respectively. The presence of lymph node metastases was associated with a higher incidence of disease recurrence. One patient with advanced local disease died from tumor bed recurrence with anaplastic transformation 18 years after the initial operation. Conclusions: Well-differentiated thyroid carcinoma is a relatively indolent tumor associated with good prognosis in young patients. Although death from this condition is rare, recurrence is frequent and longterm followup is necessary.
    View less >
    Journal Title
    Journal of the American College of Surgeons
    Volume
    194
    Issue
    6
    DOI
    https://doi.org/10.1016/S1072-7515(02)01139-0
    Subject
    Clinical sciences
    Publication URI
    http://hdl.handle.net/10072/21784
    Collection
    • Journal articles

    Footer

    Disclaimer

    • Privacy policy
    • Copyright matters
    • CRICOS Provider - 00233E

    Tagline

    • Gold Coast
    • Logan
    • Brisbane - Queensland, Australia
    First Peoples of Australia
    • Aboriginal
    • Torres Strait Islander