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dc.contributor.authorL. Seib, Kateen_US
dc.contributor.authorR.A. Peak, Ianen_US
dc.contributor.authorP. Jennings, Michaelen_US
dc.date.accessioned2017-04-24T14:51:48Z
dc.date.available2017-04-24T14:51:48Z
dc.date.issued2002en_US
dc.date.modified2014-02-28T02:38:55Z
dc.identifier.issn09288244en_US
dc.identifier.doi10.1111/j.1574-695X.2002.tb00548.xen_US
dc.identifier.urihttp://hdl.handle.net/10072/22119
dc.description.abstractA repetitive DNA motif was used as a marker to identify novel genes in the mucosal pathogen Moraxella catarrhalis. There is a high prevalence of such repetitive motifs in virulence genes that display phase variable expression. Two repeat containing loci were identified using a digoxigenin-labelled 5P-(CAAC)6-3'P oligonucleotide probe. The repeats are located in the methylase components of two distinct type III restriction-modification (R-M) systems. We suggest that the phase variable nature of these R-M systems indicates that they have an important role in the biology of M. catarrhalis.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_US
dc.languageEnglishen_US
dc.language.isoen_US
dc.publisherWiley-Blackwell Publishing Ltd.en_US
dc.publisher.placeUnited Kingdomen_US
dc.relation.ispartofpagefrom159en_US
dc.relation.ispartofpageto165en_US
dc.relation.ispartofissue2en_US
dc.relation.ispartofjournalFEMS Immunology and Medical Microbiologyen_US
dc.relation.ispartofvolume32en_US
dc.subject.fieldofresearchcode321010en_US
dc.titlePhase variable restriction-modification systems in Moraxella catarrhalisen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.date.issued2002
gro.hasfulltextNo Full Text


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