A new setup for the generation and studies of mono-disperse microbiological aerosols in medical-and-biological research
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A setup for the generation and studies of mono-disperse microbiological aerosols is described in the paper. Coefficients of 3 microm aerosol deposition in the respiratory tract of mice and rats were refined by using the above setup. The probability of deposition of such particles in the trachea and lungs of mice was proven to be equal to 1.2 +/- 0.1% and 2.6 +/- 0.2%, respectively. The probability for rats was equal to 3.2 +/- 0.2 and 11.8 +/- 0.9%, respectively. The distribution of deposited aerosol particles was determined by electron microscopy.
Rossiiskaya Akademiya Meditsinskikh Nauk. Vestnik