Isolation, structure determination, and biological activity of a novel alkaloid, perophoramidine, from the Philippine ascidian Perophora namei
Author(s)
A. Davis, Rohan
M. Verbitski, Sheryl
L. Mayne, Charles
P. Concepcion, Gisela
M. Ireland, Chris
Griffith University Author(s)
Year published
2002
Metadata
Show full item recordAbstract
Chem. investigation of the Philippine ascidian Perophora namei has resulted in the isolation of a novel polycyclic alkaloid, perophoramidine (I). The structure of I was detd. by the interpretation of 1D/2D NMR and MS data. Dehalogenation of perophoramidine by ammonium formate catalyzed transfer hydrogenation confirmed the type and no. of halogen atoms present in I.Chem. investigation of the Philippine ascidian Perophora namei has resulted in the isolation of a novel polycyclic alkaloid, perophoramidine (I). The structure of I was detd. by the interpretation of 1D/2D NMR and MS data. Dehalogenation of perophoramidine by ammonium formate catalyzed transfer hydrogenation confirmed the type and no. of halogen atoms present in I.
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Journal Title
Journal of Organic Chemistry
Volume
67
Publisher URI
Copyright Statement
© 2002 American Chemical Society. Self-archiving of the author-manuscript version is not yet supported by this publisher.
Subject
Medicinal and Biomolecular Chemistry
Organic Chemistry