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  • Isolation, structure determination, and biological activity of a novel alkaloid, perophoramidine, from the Philippine ascidian Perophora namei

    Author(s)
    A. Davis, Rohan
    M. Verbitski, Sheryl
    L. Mayne, Charles
    P. Concepcion, Gisela
    M. Ireland, Chris
    Griffith University Author(s)
    Davis, Rohan A.
    Year published
    2002
    Metadata
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    Abstract
    Chem. investigation of the Philippine ascidian Perophora namei has resulted in the isolation of a novel polycyclic alkaloid, perophoramidine (I). The structure of I was detd. by the interpretation of 1D/2D NMR and MS data. Dehalogenation of perophoramidine by ammonium formate catalyzed transfer hydrogenation confirmed the type and no. of halogen atoms present in I.Chem. investigation of the Philippine ascidian Perophora namei has resulted in the isolation of a novel polycyclic alkaloid, perophoramidine (I). The structure of I was detd. by the interpretation of 1D/2D NMR and MS data. Dehalogenation of perophoramidine by ammonium formate catalyzed transfer hydrogenation confirmed the type and no. of halogen atoms present in I.
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    Journal Title
    Journal of Organic Chemistry
    Volume
    67
    Publisher URI
    https://pubs.acs.org/toc/joceah/67/20
    DOI
    https://doi.org/10.1002/chin.200310194
    Copyright Statement
    © 2002 American Chemical Society. Self-archiving of the author-manuscript version is not yet supported by this publisher.
    Subject
    Medicinal and Biomolecular Chemistry
    Organic Chemistry
    Publication URI
    http://hdl.handle.net/10072/22217
    Collection
    • Journal articles

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