• myGriffith
    • Staff portal
    • Contact Us⌄
      • Future student enquiries 1800 677 728
      • Current student enquiries 1800 154 055
      • International enquiries +61 7 3735 6425
      • General enquiries 07 3735 7111
      • Online enquiries
      • Staff phonebook
    View Item 
    •   Home
    • Griffith Research Online
    • Journal articles
    • View Item
    • Home
    • Griffith Research Online
    • Journal articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

  • All of Griffith Research Online
    • Communities & Collections
    • Authors
    • By Issue Date
    • Titles
  • This Collection
    • Authors
    • By Issue Date
    • Titles
  • Statistics

  • Most Popular Items
  • Statistics by Country
  • Most Popular Authors
  • Support

  • Contact us
  • FAQs
  • Admin login

  • Login
  • Cytotoxic isoquinoline quinones from sponges of the genus Petrosia.

    Thumbnail
    View/Open
    37321_1.pdf (94.25Kb)
    Author(s)
    Sandoval, IT
    Davis, RA
    Bugni, TS
    Concepcion, GP
    Harper, MK
    Ireland, CM
    Griffith University Author(s)
    Davis, Rohan A.
    Year published
    2004
    Metadata
    Show full item record
    Abstract
    Bioassay-guided fractionation of two Philippine sponges of the genus Petrosia has resulted in the isolation of the novel natural product cribrostatin 7 (I) and the known compds. renierone (II) and O-demethylrenierone (III). The structures of these isoquinoline quinones were detd. by interpretation of spectroscopic data. Compds. I, II and III were cytotoxic against the HCT 116 human colon carcinoma cell line with IC50 values of 45, 24 and 34 mg/mL, resp.Bioassay-guided fractionation of two Philippine sponges of the genus Petrosia has resulted in the isolation of the novel natural product cribrostatin 7 (I) and the known compds. renierone (II) and O-demethylrenierone (III). The structures of these isoquinoline quinones were detd. by interpretation of spectroscopic data. Compds. I, II and III were cytotoxic against the HCT 116 human colon carcinoma cell line with IC50 values of 45, 24 and 34 mg/mL, resp.
    View less >
    Journal Title
    Natural Product Research
    Volume
    18
    Issue
    1
    Publisher URI
    http://www.tandf.co.uk/journals/titles/14786419.asp
    DOI
    https://doi.org/10.1080/1057563031000122130
    Copyright Statement
    © 2004 Taylor & Francis. Please refer to the journal's website for access to the definitive, published version. This is the author-manuscript version of the paper. Reproduced in accordance with the copyright policy of the publisher.
    Publication URI
    http://hdl.handle.net/10072/22219
    Collection
    • Journal articles

    Footer

    Disclaimer

    • Privacy policy
    • Copyright matters
    • CRICOS Provider - 00233E

    Tagline

    • Gold Coast
    • Logan
    • Brisbane - Queensland, Australia
    First Peoples of Australia
    • Aboriginal
    • Torres Strait Islander