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dc.contributor.authorHamidin, Nasrulen_US
dc.contributor.authorYu, Jimmyen_US
dc.contributor.authorConnell, Desen_US
dc.contributor.editorMogens Henze (Editor-in-Chief)en_US
dc.date.accessioned2017-04-24T09:04:25Z
dc.date.available2017-04-24T09:04:25Z
dc.date.issued2008en_US
dc.date.modified2011-11-03T06:15:33Z
dc.identifier.issn00431354en_US
dc.identifier.doi10.1016/j.watres.2008.02.029en_AU
dc.identifier.urihttp://hdl.handle.net/10072/22483
dc.description.abstractThe presence of chlorinated disinfection by-products (DBPs) in drinking water is a public health issue, due to their possible adverse health effects on humans. To gauge the risk of chlorinated DBPs on human health, a risk assessment of chloroform (TCM), bromodichloromethane (BDCM), dibromochloromethane (DBCM), bromoform (TBM), dichloroacetic acid (DCAA) and trichloroacetic acid (TCAA) in drinking water was carried out using probabilistic techniques. Literature data on exposure concentrations from more than 15 different countries and adverse health effects on test animals as well as human epidemiological studies were used. The risk assessment showed no overlap between the highest human exposure dose (EXPD) and the lowest human equivalent dose (HED) from animal test data, for TCM, BDCM, DBCM, TBM, DCAA and TCAA. All the HED values were approximately 104 to 105 times higher than the 95th percentiles of EXPD. However, from the human epidemiology data, there was a positive overlap between the highest EXPD and the lifetime average daily doses (LADDH) for TCM, BDCM, DCAA and TCAA. This suggests that there are possible adverse health risks such as a small increased incidence of cancers in males and developmental effects on infants. However, the epidemiological data comprised several risk factors and exposure classification levels, which may affect the overall results.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherPergamonen_US
dc.publisher.placeUnited Kingdomen_US
dc.relation.ispartofstudentpublicationNen_AU
dc.relation.ispartofpagefrom3263en_US
dc.relation.ispartofpageto3274en_US
dc.relation.ispartofissue13en_US
dc.relation.ispartofjournalWater Researchen_US
dc.relation.ispartofvolume42en_US
dc.rights.retentionNen_AU
dc.subject.fieldofresearchEnvironmental Impact Assessmenten_US
dc.subject.fieldofresearchcode050204en_US
dc.titleHuman health risk assessment of chlorinated disinfection by-products in drinking water using a probabilistic approachen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.facultyGriffith Health, School of Pharmacyen_US
gro.date.issued2008
gro.hasfulltextNo Full Text


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