Novel Cytotoxic thiodiketopiperazine derivatives from a Tilachlidium sp.

Feng, YJ; Blunt, JW; Cole, ALJ; Munro, MHG

doi:10.1021/np030326w

Author(s)

Feng, YJ

Blunt, JW

Cole, ALJ

Munro, MHG

Griffith University Author(s)

Feng, Yun J.

Year published

2004

Metadata

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Abstract

Three novel thiodiketopiperazine derivatives, T988 A, B, and C (1-3), were isolated from a Tilachlidium sp. Their structures were elucidated by spectroscopic analyses using various 1D and 2D NMR techniques. All the compounds showed potent cytotoxicity against cultured P388 leukemia cells.Three novel thiodiketopiperazine derivatives, T988 A, B, and C (1-3), were isolated from a Tilachlidium sp. Their structures were elucidated by spectroscopic analyses using various 1D and 2D NMR techniques. All the compounds showed potent cytotoxicity against cultured P388 leukemia cells.
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Journal Title

Journal of Natural Products

Volume

Issue

Publisher URI

http://pubs.acs.org/journal/jnprdf

DOI

https://doi.org/10.1021/np030326w

Copyright Statement

© 2004 American Chemical Society. Self-archiving of the author-manuscript version is not yet supported by this publisher. The contents of this journal can be freely accessed online via the ACS web page [? months] after publication. Use hypertext link above to access the ACS website.

Subject

Chemical sciences

Biological sciences

Biomedical and clinical sciences

Publication URI

http://hdl.handle.net/10072/22617

Collection

Journal articles