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dc.contributor.authorGedrange, T
dc.contributor.authorMai, R
dc.contributor.authorMack, F
dc.contributor.authorZietek, M
dc.contributor.authorBorsos, G
dc.contributor.authorVegh, A
dc.contributor.authorSpassov, A
dc.contributor.authorGredes, T
dc.date.accessioned2017-05-03T15:16:39Z
dc.date.available2017-05-03T15:16:39Z
dc.date.issued2008
dc.date.modified2010-11-02T07:04:31Z
dc.identifier.issn0867-5910
dc.identifier.urihttp://hdl.handle.net/10072/23347
dc.description.abstractSuitable tissue fixation is indispensable to histological analysis. This investigation, therefore, sought to evaluate changes of shape and size of bone specimens and remodelled bone substitute material following different fixation methods. Mandibular bones of 9 pigs (Sus scrofa domesticus) served as specimens. Two mandibular premolars were extracted respectively and the extraction alveoli were filled with synthetic bone substitute material. The samples were collected after 70 days. Fixation of 6 specimens respectively was done for 7 days in 4% formalin (formaldehyde), 70% ethanol and glycerol at 18àroom temperature. The samples were radiographically examined before and after fixation using a reference specimen and subsequently underwent histological analysis. After fixation in formalin, the samples showed no size changes. After fixation in glycerol, morphological analysis revealed minor shape changes. Fixation in ethanol causes shrinking of the tissue specimens. Histological inspection of the tissues shows no morphological changes except slight shrinking. In conclusion there is no universal fixative that could met all requirements and permited proper examination without affecting tissues or bone specimens.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent171007 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoeng
dc.publisherPolskie Towarzystwo Fizjologiczne
dc.publisher.placePoland
dc.publisher.urihttp://www.jpp.krakow.pl/
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom87
dc.relation.ispartofpageto94
dc.relation.ispartofissueSUPPL 5
dc.relation.ispartofjournalJournal of Physiology and Pharmacology
dc.relation.ispartofvolume59
dc.rights.retentionY
dc.subject.fieldofresearchDentistry not elsewhere classified
dc.subject.fieldofresearchPharmacology and pharmaceutical sciences
dc.subject.fieldofresearchMedical physiology
dc.subject.fieldofresearchcode320399
dc.subject.fieldofresearchcode3214
dc.subject.fieldofresearchcode3208
dc.titleEvaluation of shape and size changes of bone and remodelled bone substitute after different fixation methods
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.rights.copyright© 2008 the Journal of Physiology and Pharmacology and the Polish Physiological Society. The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
gro.date.issued2008
gro.hasfulltextFull Text
gro.griffith.authorMack, Florian


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