dc.contributor.author | Morrison, Brian J | |
dc.contributor.author | Schmidt, Chris W | |
dc.contributor.author | Lakhani, Sunil R | |
dc.contributor.author | Reynolds, Brent A | |
dc.contributor.author | Lopez, J Alejandro | |
dc.contributor.editor | Lewis A Chodosh (Editor-in-Chief) | |
dc.date.accessioned | 2017-05-03T14:25:40Z | |
dc.date.available | 2017-05-03T14:25:40Z | |
dc.date.issued | 2008 | |
dc.date.modified | 2009-09-03T07:17:33Z | |
dc.identifier.issn | 1465-5411 | |
dc.identifier.doi | 10.1186/bcr2111 | |
dc.identifier.uri | http://hdl.handle.net/10072/23616 | |
dc.description.abstract | The concept of cancer stem cells responsible for tumour origin, maintenance, and resistance to treatment has gained prominence in the field of breast cancer research. The therapeutic targeting of these cells has the potential to eliminate residual disease and may become an important component of a multimodality treatment. Recent improvements in immunotherapy targeting of tumour associated antigens have advanced the prospect of targeting breast cancer stem cells, an approach that might lead to more meaningful clinical remissions. Here, we review the role of stem cells in the healthy breast, the role of breast cancer stem cells in disease, and the potential to target these cells. | |
dc.description.peerreviewed | Yes | |
dc.description.publicationstatus | Yes | |
dc.format.extent | 118142 bytes | |
dc.format.mimetype | application/pdf | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | BioMed Central Ltd. | |
dc.publisher.place | United Kingdom | |
dc.publisher.uri | http://breast-cancer-research.com/content/10/4/210/abstract/ | |
dc.relation.ispartofstudentpublication | Y | |
dc.relation.ispartofpagefrom | 1 | |
dc.relation.ispartofpageto | 14 | |
dc.relation.ispartofissue | 4 | |
dc.relation.ispartofjournal | Breast Cancer Research (Online Edition) | |
dc.relation.ispartofvolume | 10 | |
dc.rights.retention | Y | |
dc.subject.fieldofresearch | Tumour immunology | |
dc.subject.fieldofresearch | Oncology and carcinogenesis | |
dc.subject.fieldofresearchcode | 320409 | |
dc.subject.fieldofresearchcode | 3211 | |
dc.title | Breast cancer stem cells: implications for therapy of breast cancer | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
dcterms.license | http://creativecommons.org/licenses/by/2.0 | |
gro.description.notepublic | Page numbers are not for citation purposes. Instead, this article has the unique article number of 10. | |
gro.rights.copyright | © 2008 Morrison, et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |
gro.date.issued | 2008 | |
gro.hasfulltext | Full Text | |
gro.griffith.author | Lopez Ramirez, Alejandro | |