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dc.contributor.authorMorrison, Brian J
dc.contributor.authorSchmidt, Chris W
dc.contributor.authorLakhani, Sunil R
dc.contributor.authorReynolds, Brent A
dc.contributor.authorLopez, J Alejandro
dc.contributor.editorLewis A Chodosh (Editor-in-Chief)
dc.date.accessioned2017-05-03T14:25:40Z
dc.date.available2017-05-03T14:25:40Z
dc.date.issued2008
dc.date.modified2009-09-03T07:17:33Z
dc.identifier.issn1465-5411
dc.identifier.doi10.1186/bcr2111
dc.identifier.urihttp://hdl.handle.net/10072/23616
dc.description.abstractThe concept of cancer stem cells responsible for tumour origin, maintenance, and resistance to treatment has gained prominence in the field of breast cancer research. The therapeutic targeting of these cells has the potential to eliminate residual disease and may become an important component of a multimodality treatment. Recent improvements in immunotherapy targeting of tumour associated antigens have advanced the prospect of targeting breast cancer stem cells, an approach that might lead to more meaningful clinical remissions. Here, we review the role of stem cells in the healthy breast, the role of breast cancer stem cells in disease, and the potential to target these cells.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent118142 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoeng
dc.publisherBioMed Central Ltd.
dc.publisher.placeUnited Kingdom
dc.publisher.urihttp://breast-cancer-research.com/content/10/4/210/abstract/
dc.relation.ispartofstudentpublicationY
dc.relation.ispartofpagefrom1
dc.relation.ispartofpageto14
dc.relation.ispartofissue4
dc.relation.ispartofjournalBreast Cancer Research (Online Edition)
dc.relation.ispartofvolume10
dc.rights.retentionY
dc.subject.fieldofresearchTumour immunology
dc.subject.fieldofresearchOncology and carcinogenesis
dc.subject.fieldofresearchcode320409
dc.subject.fieldofresearchcode3211
dc.titleBreast cancer stem cells: implications for therapy of breast cancer
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons.org/licenses/by/2.0
gro.description.notepublicPage numbers are not for citation purposes. Instead, this article has the unique article number of 10.
gro.rights.copyright© 2008 Morrison, et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
gro.date.issued2008
gro.hasfulltextFull Text
gro.griffith.authorLopez Ramirez, Alejandro


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