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dc.contributor.authorWatson, GS
dc.contributor.authorWatson, JA
dc.contributor.editorJohansson, LSO
dc.contributor.editorAndersen, JN
dc.contributor.editorGothelid, M
dc.contributor.editorHelmersson, U
dc.contributor.editorMontelius, L
dc.contributor.editorRubel, M
dc.contributor.editorSetina, J
dc.contributor.editorWernersson, LE
dc.date.accessioned2017-05-03T11:27:10Z
dc.date.available2017-05-03T11:27:10Z
dc.date.issued2008
dc.date.modified2009-05-27T08:46:30Z
dc.identifier.issn1742-6588
dc.identifier.doi10.1088/1742-6596/100/5/052041
dc.identifier.urihttp://hdl.handle.net/10072/24104
dc.description.abstractThe ability to interact with live cells in vitro in combination with either sequential image acquisition or continuous force sensing provide the means for tracking the dynamics of intra- or inter-cell processes. The former operational mode is relatively slow and is most suitable for events where the temporal evolution takes place on a time scale of several minutes to hours. For instance, aspects of cytoskeletal dynamics, cell motility or conformational response to external stimuli fall into this category. In this study we demonstrate cell responses from exposure to cytochalasin, glutaraldehyde and a tetrazolium salt. Significant changes in mechanical properties and structural features are observed on time scales up to 3 hrs. In addition, comparative studies of cytoskeletal components of dried and living cells are undertaken.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent268571 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoeng
dc.publisherIOP Publishing Limited
dc.publisher.placeUnited Kingdom
dc.publisher.urihttps://iopscience-iop-org.libraryproxy.griffith.edu.au/article/10.1088/1742-6596/100/5/052041
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom1
dc.relation.ispartofpageto4
dc.relation.ispartofjournalJournal of Physics: Conference Series
dc.relation.ispartofvolume100
dc.rights.retentionY
dc.subject.fieldofresearchCondensed matter physics
dc.subject.fieldofresearchOther physical sciences
dc.subject.fieldofresearchHistory, heritage and archaeology
dc.subject.fieldofresearchcode5104
dc.subject.fieldofresearchcode5199
dc.subject.fieldofresearchcode43
dc.titleAnalysis of cytoskeletal features in dried and living cells and slow dynamic experiments using Atomic Force Microscopy
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.rights.copyright© 2008 Institute of Physics Publishing. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
gro.date.issued2008
gro.hasfulltextFull Text
gro.griffith.authorWatson, Jolanta A.
gro.griffith.authorWatson, Gregory S.


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