Show simple item record

dc.contributor.authorJ. Lewis, Stephen
dc.contributor.authorL. Smith, Adrian
dc.contributor.authorG. Neduvelil, Joseph
dc.contributor.authorStevenson, G.
dc.contributor.authorJ. Lindon, Matthew
dc.contributor.authorBrian Jones, A.
dc.contributor.authorS. Shearman, Mark
dc.contributor.authorBeher, Dirk
dc.contributor.authorClarke, Earl
dc.contributor.authorD. Best, Jonathan
dc.contributor.authorE. Peachey, James
dc.contributor.authorHarrison, Timothy
dc.contributor.authorLuis Castro, J.
dc.date.accessioned2017-05-03T16:57:53Z
dc.date.available2017-05-03T16:57:53Z
dc.date.issued2005
dc.date.modified2009-07-27T07:01:51Z
dc.identifier.issn0960894X
dc.identifier.doi10.1016/j.bmcl.2004.10.062
dc.identifier.urihttp://hdl.handle.net/10072/24885
dc.description.abstractA new series of y-secretase inhibitors was developed from an in-house screening hit based on a benzobicyclo[4.2.1]nonane core. Lead optimisation studies led to the development of a series of potent inhibitors and in vivo efficacy was demonstrated.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.publisher.placeUnited Kingdom
dc.publisher.urihttp://www.sciencedirect.com/science/journal/0960894X
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom373
dc.relation.ispartofpageto378
dc.relation.ispartofissue2
dc.relation.ispartofjournalBioorganic & Medicinal Chemistry Letters
dc.relation.ispartofvolume15
dc.rights.retentionY
dc.subject.fieldofresearchMedical Biochemistry and Metabolomics not elsewhere classified
dc.subject.fieldofresearchMedicinal and Biomolecular Chemistry
dc.subject.fieldofresearchOrganic Chemistry
dc.subject.fieldofresearchPharmacology and Pharmaceutical Sciences
dc.subject.fieldofresearchcode110199
dc.subject.fieldofresearchcode0304
dc.subject.fieldofresearchcode0305
dc.subject.fieldofresearchcode1115
dc.titleA novel series of potent γ-secretase inhibitors based on a benzobicyclo[4.2.1]nonane core
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2005
gro.hasfulltextNo Full Text
gro.griffith.authorStevenson, Graeme I.


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record