Parvistemins A–D, a new type of dimeric phenylethyl benzoquinones from Stemona parviflora Wright
Author(s)
Yang, Xinzhou
A.M. Gulder, Tobias
Reichert, Matthias
Tang, Chunping
Ke, Changqiang
Ye, Yang
Bringmann, Gerhard
Griffith University Author(s)
Year published
2007
Metadata
Show full item recordAbstract
Four naturally occurring dimeric phenylethyl benzoquinones, parvistemins A-D, were isolated from the aerial parts of Stemona parviflora Wright. Their constitutions were established by spectroscopic methods. Due to restricted rotation about the central biaryl axis, the compounds are chiral, although racemic. Their two respective atropo-enantiomers were resolved by HPLC on a chiral phase and were stereochemically characterized online, in hyphenation with circular dichroism (CD) spectroscopy (LC-CD coupling), combined with quantum chemical CD calculations.Four naturally occurring dimeric phenylethyl benzoquinones, parvistemins A-D, were isolated from the aerial parts of Stemona parviflora Wright. Their constitutions were established by spectroscopic methods. Due to restricted rotation about the central biaryl axis, the compounds are chiral, although racemic. Their two respective atropo-enantiomers were resolved by HPLC on a chiral phase and were stereochemically characterized online, in hyphenation with circular dichroism (CD) spectroscopy (LC-CD coupling), combined with quantum chemical CD calculations.
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Journal Title
Tetrahedron
Volume
63
Issue
22
Subject
Medicinal and Biomolecular Chemistry
Organic Chemistry