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  • Finding Rule Groups to Classify High Dimensional Gene Expression Datasets

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    Author(s)
    An, Jiyuan
    Chen, Yi-Ping Phoebe
    Griffith University Author(s)
    An, Jay
    Year published
    2006
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    Abstract
    Microarray data provides quantitative information about the transcription profile of cells. To analyze microarray datasets, methodology of machine learning has increasingly attracted bioinformatics researchers. Some approaches of machine learning are widely used to classify and mine biological datasets. However, many gene expression datasets are extremely high dimensionality, traditional machine learning methods can not be applied effectively and efficiently. This paper proposes a robust algorithm to find out rule groups to classify gene expression datasets. Unlike the most classification algorithms, which select dimensions ...
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    Microarray data provides quantitative information about the transcription profile of cells. To analyze microarray datasets, methodology of machine learning has increasingly attracted bioinformatics researchers. Some approaches of machine learning are widely used to classify and mine biological datasets. However, many gene expression datasets are extremely high dimensionality, traditional machine learning methods can not be applied effectively and efficiently. This paper proposes a robust algorithm to find out rule groups to classify gene expression datasets. Unlike the most classification algorithms, which select dimensions (genes) heuristically to form rules groups to identify classes such as cancerous and normal tissues, our algorithm guarantees finding out best-k dimensions (genes), which are most discriminative to classify samples in different classes, to form rule groups for the classification of expression datasets. Our experiments show that the rule groups obtained by our algorithm have higher accuracy than that of other classification approaches
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    Conference Title
    Proceedings: The 18th International Conference of Pattern Recognition
    Publisher URI
    http://ieeexplore.ieee.org/servlet/opac?punumber=11159
    DOI
    https://doi.org/10.1109/ICPR.2006.564
    Copyright Statement
    © 2006 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.
    Publication URI
    http://hdl.handle.net/10072/25630
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    • Conference outputs

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