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  • Odor Detection Performance in Hypothyroid and Euthyroid Rats

    Author(s)
    Brosvic, GM
    Risser, JM
    Mackay-Sim, A
    Doty, RL
    Griffith University Author(s)
    Mackay-Sim, Alan
    Year published
    1996
    Metadata
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    Abstract
    The influence of hypothyroidism on the odor detection ability of male Long-Evans rats was determined using high-precision olfactometry and a go/no-go operant task. Nonparametric signal detection measures of sensitivity and responsitivity, as well as measures of S + response latency, the number of aborted trials, and session time were obtained in daily 200-trial test sessions prior to, during, and after 50 days of maintenance on 0.1% propylthiouracil (PTU). Similar determinations were made in control animals. Neither odor detection nor associated nonsensory performance measures were influenced by hypothyroidism. These results ...
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    The influence of hypothyroidism on the odor detection ability of male Long-Evans rats was determined using high-precision olfactometry and a go/no-go operant task. Nonparametric signal detection measures of sensitivity and responsitivity, as well as measures of S + response latency, the number of aborted trials, and session time were obtained in daily 200-trial test sessions prior to, during, and after 50 days of maintenance on 0.1% propylthiouracil (PTU). Similar determinations were made in control animals. Neither odor detection nor associated nonsensory performance measures were influenced by hypothyroidism. These results suggest that PTU-induced hypothyroidism does not affect the odor detection performance of rats.
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    Journal Title
    Physiology and Behavior
    Volume
    59
    Publisher URI
    http://www.sciencedirect.com/science/journal/00319384
    DOI
    https://doi.org/10.1016/0031-9384(95)00145-X
    Subject
    Biological sciences
    Biomedical and clinical sciences
    Psychology
    Publication URI
    http://hdl.handle.net/10072/25752
    Collection
    • Journal articles

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