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dc.contributor.authorUlett, GC
dc.contributor.authorKetheesan, N
dc.contributor.authorClair, TW
dc.contributor.authorMcElnea, CL
dc.contributor.authorBarnes, JL
dc.contributor.authorHirst, RG
dc.date.accessioned2017-09-05T05:36:58Z
dc.date.available2017-09-05T05:36:58Z
dc.date.issued2002
dc.date.modified2009-09-29T23:14:42Z
dc.identifier.issn0019-9567
dc.identifier.doi10.1128/IAI.70.7.3953-3958.2002
dc.identifier.urihttp://hdl.handle.net/10072/25835
dc.description.abstractCytokine mRNA levels were assessed in Burkholderia pseudomallei-susceptible BALB/c mice and B. pseudomallei- resistant C57BL/6 mice following administration of a sublethal dose of less virulent (LV) B. pseudomallei, a candidate immunogen tested for protection against a highly virulent (HV) challenge. Compared on the basis of the bacterial loads, the cytokine patterns induced by HV and LV B. pseudomallei were similar, involving gamma interferon, interleukin-10, and other cytokines. Partial cross-protection between B. pseudomallei strains is shown to be associated with cytokine profiles involving both type 1 and type 2 cytokines.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherThe American Society for Microbiology
dc.publisher.placeUSA
dc.relation.ispartofpagefrom3953
dc.relation.ispartofpageto3958
dc.relation.ispartofissue7
dc.relation.ispartofjournalInfection and Immunity
dc.relation.ispartofvolume70
dc.subject.fieldofresearchBiological sciences
dc.subject.fieldofresearchAgricultural, veterinary and food sciences
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchMedical bacteriology
dc.subject.fieldofresearchcode31
dc.subject.fieldofresearchcode30
dc.subject.fieldofresearchcode32
dc.subject.fieldofresearchcode320701
dc.titleAnalogous Cytokine Responses to Burkholderia pseudomallei Strains Contrasting in Virulence Correlate with Partial Cross-Protection in Immunized Mice
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2002 American Society for Microbiology. The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
gro.date.issued2002
gro.hasfulltextFull Text
gro.griffith.authorUlett, Glen C.


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