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dc.contributor.authorPatel, Aen_US
dc.contributor.authorMacMahon, Sen_US
dc.contributor.authorChalmers, Jen_US
dc.contributor.authorNeal, Ben_US
dc.contributor.authorBillot, Len_US
dc.contributor.authorWoodward, Men_US
dc.contributor.authorMarre, Men_US
dc.contributor.authorCooper, Men_US
dc.contributor.authorGlasziou, Pen_US
dc.contributor.authorGrobbee, DEen_US
dc.contributor.authorHamet, Pen_US
dc.contributor.authorHarrap, Sen_US
dc.contributor.authorHeller, Sen_US
dc.contributor.authorLiu, LSen_US
dc.contributor.authorMancia, Gen_US
dc.contributor.authorMogensen, CEen_US
dc.contributor.authorPan, CYen_US
dc.contributor.authorPoulter, Nen_US
dc.contributor.authorRodgers, Aen_US
dc.contributor.authorWilliams, Ben_US
dc.contributor.authorBompoint, Sen_US
dc.contributor.authorGalan, Ben_US
dc.contributor.authorJoshi, R.en_US
dc.contributor.authorTravert, Fen_US
dc.contributor.authorFerrannini, Een_US
dc.contributor.authorHamet, Pen_US
dc.contributor.authorCollins, Ren_US
dc.contributor.authorHolman, Ren_US
dc.contributor.authorSandercock, Pen_US
dc.contributor.authorSleight, Pen_US
dc.contributor.authorFulcher, Gen_US
dc.contributor.authorAdams, Men_US
dc.contributor.authorBranley, Men_US
dc.contributor.authorJenkins, Ben_US
dc.contributor.authorLouis, Den_US
dc.contributor.authorLowe, Hen_US
dc.contributor.authorLuo, Wen_US
dc.contributor.authorMcCormack, Aen_US
dc.contributor.authorMitchell, Pen_US
dc.contributor.authorOng, Sen_US
dc.contributor.authorPollock, Cen_US
dc.contributor.authorWatson, Jen_US
dc.contributor.authorWong, Ten_US
dc.contributor.authorBillot, Len_US
dc.contributor.authorBompoint, Sen_US
dc.contributor.authorColman, Sen_US
dc.contributor.authorFrancis, Len_US
dc.contributor.authorHeritier, Sen_US
dc.contributor.authorLi, Qen_US
dc.contributor.authorNinomiya, Ten_US
dc.contributor.authorPillai, Aen_US
dc.contributor.authorTravert, Fen_US
dc.contributor.authorBaksi, Aen_US
dc.contributor.authorBao, YQen_US
dc.contributor.authorCutfield, Ren_US
dc.contributor.authorDumas, Ren_US
dc.contributor.authorFovenyi, Jen_US
dc.contributor.authorFu, HJen_US
dc.contributor.authorHuang, Hen_US
dc.contributor.authorJia, PHen_US
dc.contributor.authorKhir, Aen_US
dc.contributor.authorKrahulec, Ben_US
dc.contributor.authorLi, CLen_US
dc.contributor.authorLi, Jen_US
dc.contributor.authorLitonjua, Aen_US
dc.contributor.authorMacIsaac, Ren_US
dc.contributor.authorPlaczkiewicz-Jankowska, Een_US
dc.contributor.authorQuirk, Sen_US
dc.contributor.authorSouthern, Sen_US
dc.contributor.authorTack, Cen_US
dc.contributor.authorTandon, Nen_US
dc.contributor.authorXu, ZRen_US
dc.contributor.authorZhang, JCen_US
dc.contributor.authorZhang, Zen_US
dc.contributor.authorZou, XMen_US
dc.contributor.authorPrato, S Delen_US
dc.contributor.authorFlynn, Sen_US
dc.contributor.authorMonaghan, Hen_US
dc.contributor.authorAllen, Sen_US
dc.contributor.authorBi, YFen_US
dc.contributor.authorCarreras, Aen_US
dc.contributor.authorCass, Aen_US
dc.contributor.authorChen, Ten_US
dc.contributor.authorCurrie, Ren_US
dc.contributor.authorDavies, Pen_US
dc.contributor.authorDu, Xen_US
dc.contributor.authorFathers, Jen_US
dc.contributor.authorGibb, Sen_US
dc.contributor.authorGirgis, Sen_US
dc.contributor.authorGraziano, Aen_US
dc.contributor.authorHeritier, Sen_US
dc.contributor.authorHibbard, Jen_US
dc.contributor.authorHough, Sen_US
dc.contributor.authorHuynh, Aen_US
dc.contributor.authorJan, Sen_US
dc.contributor.authorJardine, Men_US
dc.contributor.authorJayne, Ken_US
dc.contributor.authorDavoren, Peteren_US
dc.contributor.authoral, eten_US
dc.date.accessioned2017-04-24T13:01:14Z
dc.date.available2017-04-24T13:01:14Z
dc.date.issued2008en_US
dc.identifier.issn00284793en_US
dc.identifier.doi10.1016/j.jvs.2008.07.045en_US
dc.identifier.urihttp://hdl.handle.net/10072/26242
dc.description.abstractThe prevalence of Type 2 diabetes is increasing rapidly and is associated with significant cardiovascular adverse effects. The authors tested the hypothesis that, in patients with type II diabetes, intensive glucose control as evidenced by lowering the glycated hemoglobin level to to =6.5% would result in lower rates of major microvascular and macrovascular events. There were 11,140 patients with Type 2 diabetes who were randomly assigned to undergo standard glucose control or intensive glucose control. Intensive glucose control was achieved with the use of gliclazide (modified release) and other drugs as required to reach a glycated hemoglobin =6.5%. Primary end points were composites of major microvascular events (new or worsening nephropathy or retinopathy) or macrovascular events (death from cardiovascular causes, non-fatal myocardial infarction, or non-fatal stroke). End points were assessed both jointly and separately.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_US
dc.languageEnglishen_US
dc.language.isoen_US
dc.publisherMassachusetts Medical Societyen_US
dc.publisher.placeUnited States of Americaen_US
dc.publisher.urihttp://www.sciencedirect.com/science/journal/07415214en_US
dc.relation.ispartofstudentpublicationNen_US
dc.relation.ispartofpagefrom2560en_US
dc.relation.ispartofpageto2572en_US
dc.relation.ispartofissue24en_US
dc.relation.ispartofjournalThe New England Journal of Medicineen_US
dc.relation.ispartofvolume358en_US
dc.rights.retentionYen_US
dc.subject.fieldofresearchcode321202en_US
dc.titleIntensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetesen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.date.issued2014-10-10T01:56:19Z
gro.hasfulltextNo Full Text


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