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dc.contributor.authorRoberts, MS
dc.contributor.authorAnissimov, YG
dc.contributor.authorGonsalvez, RA
dc.date.accessioned2017-05-03T15:13:51Z
dc.date.available2017-05-03T15:13:51Z
dc.date.issued2001
dc.date.modified2009-11-06T05:51:21Z
dc.identifier.issn0731-3829
dc.identifier.doi10.1081/CUS-120001859
dc.identifier.urihttp://hdl.handle.net/10072/26426
dc.description.abstractA number of mathematical models have been used to describe percutaneous absorption kinetics. In general, most of these models have used either diffusion-based or compartmental equations. The object of any mathematical model is to a) be able to represent the processes associated with absorption accurately, b) be able to describe/summarize experimental data with parametric equations or moments, and c) predict kinetics under varying conditions. However, in describing the processes involved, some developed models often suffer from being of too complex a form to be practically useful. In this chapter, we attempt to approach the issue of mathematical modeling in percutaneous absorption from four perspectives. These are to a) describe simple practical models, b) provide an overview of the more complex models, c) summarize some of the more important/useful models used to date, and d) examine some practical applications of the models.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherTaylor & Francis Inc.
dc.publisher.placeUnited States
dc.relation.ispartofpagefrom221
dc.relation.ispartofpageto270
dc.relation.ispartofissue2
dc.relation.ispartofjournalCutaneous and Ocular Toxicology
dc.relation.ispartofvolume20
dc.subject.fieldofresearchPharmacology and pharmaceutical sciences
dc.subject.fieldofresearchcode3214
dc.titleMathematical models in percutaneous absorption
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2001
gro.hasfulltextNo Full Text
gro.griffith.authorAnissimov, Yuri G.


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