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dc.contributor.authorCobbold, C
dc.contributor.authorMonaco, AP
dc.contributor.authorSivaprasadarao, A
dc.contributor.authorPonnambalam, S
dc.date.accessioned2017-05-03T15:03:55Z
dc.date.available2017-05-03T15:03:55Z
dc.date.issued2003
dc.date.modified2009-12-22T03:06:38Z
dc.identifier.issn0962-8924
dc.identifier.doi10.1016/j.tcb.2003.10.008
dc.identifier.urihttp://hdl.handle.net/10072/26481
dc.description.abstractTransmembrane domain (TMD) proteins comprise a major group of proteins that perform a wide range of functions and act to translate extracellular signals to intracellular responses. They include G-protein coupled receptors (GPCRs), growth factor receptors, ion channels, transporters and metabolic enzymes. In this review, we focus on the current understanding of trafficking of mutant membrane proteins in human disease and speculate on therapeutic strategies.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.publisher.placeUnited Kingdom
dc.publisher.urihttp://www.cell.com/trends/cell-biology/home
dc.relation.ispartofpagefrom639
dc.relation.ispartofpageto647
dc.relation.ispartofissue12
dc.relation.ispartofjournalTrends in Cell Biology
dc.relation.ispartofvolume13
dc.subject.fieldofresearchBiological sciences
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchcode31
dc.subject.fieldofresearchcode32
dc.titleAberrant trafficking of transmembrane proteins in human disease
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2003
gro.hasfulltextNo Full Text
gro.griffith.authorCobbold, Christian J.


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