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dc.contributor.authorvan Rooyen, Jacquesen_US
dc.contributor.authorEsterhuyse, Adriaanen_US
dc.contributor.authorEngelbrecht, Anna-Marten_US
dc.contributor.authordu Toit, Eugeneen_US
dc.date.accessioned2017-04-24T13:06:16Z
dc.date.available2017-04-24T13:06:16Z
dc.date.issued2008en_US
dc.identifier.issn09647058en_US
dc.identifier.urihttp://hdl.handle.net/10072/26917
dc.description.abstractNumerous studies have reported the protective properties of carotenoid supplementation against skin and eye associated diseases. However, conflicting data concerning the efficacy of ߭carotene in the pathogenesis of cancers and cardiovascular disease exist. It has been shown that ߭carotene is an effective antioxidant on its own or in combination with other antioxidants. Red palm oil (RPO) is a potent anti-oxidant rich oil which consists of carotenoids, tocopherols, tocotrienols and lycopenes as well as lipid fractions such as squalene, saturated and unsaturated fatty acids (which maximize absorption of these anti-oxidants) and Co-enzyme Q10. a and ߭carotene account for more than 90% of the total carotene in RPO. It is known that ischaemia/reperfusion-induced injury causes an imbalance in oxygen supply which can lead to oxidative stress in the heart. It has been shown that the mitogen-activated protein kinases (MAPKs), PKB/Akt and the NO-cGMP all play vital roles in ischaemia/ reperfusion injury in the heart. Therefore, our review mainly focuses on the signaling pathways involved in functional recovery induced by a natural carotenoid oil after ischaemia/reperfusion injuryen_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_US
dc.format.extent154496 bytes
dc.format.extent20002 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.languageEnglishen_US
dc.language.isoen_US
dc.publisherHEC Pressen_US
dc.publisher.placeAustraliaen_US
dc.publisher.urihttp://apjcn.nhri.org.tw/server/APJCN/Volume17/vol17suppl.1/316-319S19-3.pdfen_US
dc.relation.ispartofstudentpublicationNen_US
dc.relation.ispartofpagefrom316en_US
dc.relation.ispartofpageto319en_US
dc.relation.ispartofjournalAsia Pacific Journal of Clinical Nutritionen_US
dc.relation.ispartofvolume17en_US
dc.rights.retentionYen_US
dc.subject.fieldofresearchCardiology (incl. Cardiovascular Diseases)en_US
dc.subject.fieldofresearchcode110201en_US
dc.titleHealth benefits of a natural carotenoid rich oil: a proposed mechanism of protection against ischaemi/reperfusion injuryen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.rights.copyrightCopyright 2008 HEC Press. The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.en_US
gro.date.issued2015-05-31T22:21:55Z
gro.hasfulltextFull Text


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