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dc.contributor.authorMcGrath, John
dc.contributor.authorEyles, Darryl
dc.contributor.authorMowry, Bryan
dc.contributor.authorYolken, Robert
dc.contributor.authorBuka, Stephen
dc.date.accessioned2017-05-03T16:58:22Z
dc.date.available2017-05-03T16:58:22Z
dc.date.issued2003
dc.date.modified2009-12-05T05:16:16Z
dc.identifier.issn0920-9964
dc.identifier.doi10.1016/S0920-9964(02)00435-8
dc.identifier.urihttp://hdl.handle.net/10072/27095
dc.description.abstractObjective: Evidence from epidemiology suggests that low maternal vitamin D may be a risk factor for schizophrenia. Method: Based on sera taken during the third trimester, we compared the level of 25 hydroxyvitamin D3 in mothers of individuals with schizophrenia or schizoaffective disorders versus mothers of unaffected controls. For each case, we selected two controls matched on race, gender and date of birth of the offspring. Results: There was no significant difference in third trimester maternal vitamin D in the entire sample (cases=26, CONTROLS=51). Within the subgroup of black individuals (n=21), there was a trend level difference in the predicted direction. Conclusions: Maternal vitamin D does not operate as a continuous graded risk factor for schizophrenia, however, the results in the black subgroup raise the possibility that below a certain critical threshold, low levels of maternal vitamin D may be associated with an increased risk of schizophrenia.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.publisher.placeNetherlands
dc.relation.ispartofpagefrom73
dc.relation.ispartofpageto78
dc.relation.ispartofissue1-2
dc.relation.ispartofjournalSchizophrenia Research
dc.relation.ispartofvolume63
dc.subject.fieldofresearchEpidemiology
dc.subject.fieldofresearchMedical and Health Sciences
dc.subject.fieldofresearchPsychology and Cognitive Sciences
dc.subject.fieldofresearchcode111706
dc.subject.fieldofresearchcode11
dc.subject.fieldofresearchcode17
dc.titleLow maternal vitamin D as a risk factor for schizophrenia: A pilot study using banked sera
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2003
gro.hasfulltextNo Full Text
gro.griffith.authorMcGrath, John J.


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