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  • The romance of balancing selection versus the sober alternatives: Let the data rule

    Author(s)
    J. McGrath, John
    Griffith University Author(s)
    McGrath, John J.
    Year published
    2006
    Metadata
    Show full item record
    Abstract
    Schizophrenia has attracted more than its fair share of evolutionary-based theories. The theories involving balancing selection are based on the assumption that the incidence of schizophrenia is invariant across time and place. Modern epidemiology allows us to reject this dogmatic belief. Once variations in the genetic and epidemiological landscape of schizophrenia are acknowledged, more productive research models can be generated.Schizophrenia has attracted more than its fair share of evolutionary-based theories. The theories involving balancing selection are based on the assumption that the incidence of schizophrenia is invariant across time and place. Modern epidemiology allows us to reject this dogmatic belief. Once variations in the genetic and epidemiological landscape of schizophrenia are acknowledged, more productive research models can be generated.
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    Journal Title
    Behavioral and Brain Sciences
    Volume
    29
    Issue
    4
    DOI
    https://doi.org/10.1017/S0140525X06349096
    Subject
    Psychiatry (incl. Psychotherapy)
    Artificial Intelligence and Image Processing
    Neurosciences
    Cognitive Sciences
    Publication URI
    http://hdl.handle.net/10072/27100
    Collection
    • Journal articles

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