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dc.contributor.authorDavies, Geoffrey
dc.contributor.authorWelham, Joy
dc.contributor.authorChant, David
dc.contributor.authorFuller Torrey, E.
dc.contributor.authorMcGrath, John
dc.date.accessioned2017-05-03T16:58:22Z
dc.date.available2017-05-03T16:58:22Z
dc.date.issued2003
dc.date.modified2009-12-05T05:18:03Z
dc.identifier.issn05867614
dc.identifier.urihttp://hdl.handle.net/10072/27108
dc.description.abstractBased on the epidemiological finding that individuals with schizophrenia tend to be born in winter/spring when compared to the general population, we examined (1) the strength and timing of this effect in Northern Hemisphere sites, and (2) the correlation between the season of birth effect size and latitude. Studies were located via electronic data sources, published citations, and letters to authors. Inclusion criteria were that studies specify the diagnostic criteria used, that studies specify the counts of schizophrenia and general population births for each month, and that subjects and the general population be drawn from the same birth years and catchment area. We extracted data from eight studies based on 126,196 patients with schizophrenia and 86,605,807 general population births and drawn from 27 Northern Hemisphere sites. Comparing winter/spring versus summer/autumn births, we found a significant excess for winter/spring births (pooled odds ratio = 1.07; 95% confidence interval 1.05, 1.08; population attributable risk = 3.3%). There was a small but significant positive correlation between the odds ratios for the season of birth comparison and latitude (r = 0.271, p < 0.005). Furthermore, the shape of the seasonality in schizophrenia births varied by latitude band. These variations may encourage researchers to generate candidate seasonally fluctuating exposures.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherOxford University Press
dc.publisher.placeUK
dc.publisher.urihttp://schizophreniabulletin.oxfordjournals.org/
dc.relation.ispartofpagefrom587
dc.relation.ispartofpageto593
dc.relation.ispartofissue3
dc.relation.ispartofjournalSchizophrenia Bulletin
dc.relation.ispartofvolume29
dc.subject.fieldofresearchEpidemiology
dc.subject.fieldofresearchMedical and Health Sciences
dc.subject.fieldofresearchPsychology and Cognitive Sciences
dc.subject.fieldofresearchcode111706
dc.subject.fieldofresearchcode11
dc.subject.fieldofresearchcode17
dc.titleA Systematic Review and Meta-analysis of Northern Hemisphere Season of Birth Studies in Schizophrenia
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2003
gro.hasfulltextNo Full Text
gro.griffith.authorMcGrath, John J.


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