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  • New Triterpene Glucosides from the Roots of Rosa laevigata Michx

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    Author(s)
    Yuan, Jing-Quan
    Yang, Xin-Zhou
    Miao, Jian-Hua
    Tang, Chun-Ping
    Ke, Chang-Qiang
    Zhang, Ji-Bao
    Ma, Xiao-Jun
    Ye, Yang
    Griffith University Author(s)
    Yang, Xinzhou
    Year published
    2008
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    Abstract
    Two new ursane-type triterpene glucosides, 2a,3a,24-trihydroxyurs-12,18-dien-28-oic acid ߭D-glucopyranosyl ester (1) and 2a,3a,23-trihydroxyurs-12,19(29)-dien-28-oic acid ߭D-glucopyranosyl ester (2), were isolated from the roots of Rosa laevigata, together with three known compounds: 2a,3߬19a-trihydroxyurs-12-en-28-oic acid ߭Dglucopyranosyl ester (3), 2a,3a,19a-trihydroxyurs-12-en-28-oic acid ߭D-glucopyranosyl ester (4) and 2a,3߬19a,23-tetrahydroxyurs-12-en-28-oic acid ߭D-glucopyranosyl ester (5). The structures of new compounds were established on the basis of detailed 1D and 2D NMR spectroscopic analyses. Compounds 2 and ...
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    Two new ursane-type triterpene glucosides, 2a,3a,24-trihydroxyurs-12,18-dien-28-oic acid ߭D-glucopyranosyl ester (1) and 2a,3a,23-trihydroxyurs-12,19(29)-dien-28-oic acid ߭D-glucopyranosyl ester (2), were isolated from the roots of Rosa laevigata, together with three known compounds: 2a,3߬19a-trihydroxyurs-12-en-28-oic acid ߭Dglucopyranosyl ester (3), 2a,3a,19a-trihydroxyurs-12-en-28-oic acid ߭D-glucopyranosyl ester (4) and 2a,3߬19a,23-tetrahydroxyurs-12-en-28-oic acid ߭D-glucopyranosyl ester (5). The structures of new compounds were established on the basis of detailed 1D and 2D NMR spectroscopic analyses. Compounds 2 and 5 exhibited modest in vitro antifungal activities against Candida albicans and C. krusei.
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    Journal Title
    Molecules
    Volume
    13
    Issue
    9
    DOI
    https://doi.org/10.3390/molecules13092229
    Copyright Statement
    © 2008 by the authors.licensee Molecular Diversity Preservation International, Basel, Switzerland. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported (CC BY-NC-SA 3.0) License (http://creativecommons.org/licenses/by-nc-sa/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited. If you alter, transform, or build upon this work, you may distribute the resulting work only under a licence identical to this one.
    Subject
    Medicinal and Biomolecular Chemistry
    Organic Chemistry
    Theoretical and Computational Chemistry
    Publication URI
    http://hdl.handle.net/10072/27202
    Collection
    • Journal articles

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