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  • Placental calcium pump: clinical-based evidence

    Author(s)
    M. Kasznica, John
    B. Petcu, Eugen
    Griffith University Author(s)
    Petcu, Eugen B.
    Year published
    2003
    Metadata
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    Abstract
    Placenta can be considered as a pump of calcium necessary for the normal development of the fetus. We believe that the location of this pump is in the placental basement membrane. The calcification of this membrane has been described only in cases of in utero fetal death. In this study we describe for the first time a case of placental calcification in a living fetus. The fetus of a normal 21-year-old pregnant woman showed heart abnormalities but the genetic analysis showed a normal male karyotype. The histology of the placenta demonstrated multiple intravillous linear and granular calcific incrustations The hemtoxylin/eosin ...
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    Placenta can be considered as a pump of calcium necessary for the normal development of the fetus. We believe that the location of this pump is in the placental basement membrane. The calcification of this membrane has been described only in cases of in utero fetal death. In this study we describe for the first time a case of placental calcification in a living fetus. The fetus of a normal 21-year-old pregnant woman showed heart abnormalities but the genetic analysis showed a normal male karyotype. The histology of the placenta demonstrated multiple intravillous linear and granular calcific incrustations The hemtoxylin/eosin stain of the sections revealed basement membrane calcific incrustations and intravillous calcium deposits. We postulate that the fetal circulation in the villi was impaired and the calcium that reached the villi from the mother was deposited at this level.
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    Journal Title
    Pediatric Pathology & Molecular Medicine
    Volume
    22
    Issue
    3
    Publisher URI
    http://informahealthcare.com/loi/pdp
    DOI
    https://doi.org/10.1080/pdp.22.3.223.227
    Subject
    Paediatrics and Reproductive Medicine
    Publication URI
    http://hdl.handle.net/10072/27505
    Collection
    • Journal articles

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