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dc.contributor.authorBrowne, H.en_US
dc.contributor.authorAdams, Lewisen_US
dc.contributor.authorSimonds, A.en_US
dc.contributor.authorMorrell, M.en_US
dc.date.accessioned2017-05-03T13:56:56Z
dc.date.available2017-05-03T13:56:56Z
dc.date.issued2003en_US
dc.date.modified2009-12-17T22:29:00Z
dc.identifier.issn09546111en_US
dc.identifier.doi10.1016/S0954-6111(03)00142-2en_AU
dc.identifier.urihttp://hdl.handle.net/10072/27665
dc.description.abstractArousals from sleep result in hyperventilation and hypocapnia that can lead to sleep apnoea. We have investigated whether sleep apnoea in the elderly is associated with more arousals compared with younger people. Additionally, the impact of arousals on daytime symptoms was noted. Four groups (n=11) of elderly (>65 years) and young (o39 years) apnoeic (EA and YA), and age-matched nonapnoeics (EN and YN) were studied. The arousal index (AI) and apnoea/hypopnoea index were determined from polysomnography. Sleepiness (Epworth Sleepiness Scale) and Quality of life (QoL, SF-36) were assessed. The mean (SD) AI was: EN 23.1 (7.6), EA 46.5 (8.8), YN 13.2 (6.6), YA 38.5 (12.1) events/h. AI was higher in the elderly (P=0.002) and in apnoeics (P=0.001); however, the increase in AI associated with sleep apnoea was not age dependent (P=0.73). The influence of sleep apnoea on sleepiness was similar in both age groups. YA but not EA reported reduced physical functioning (P=0.04), vitality (P=0.007) and general health (P=0.04) compared to non-apnoeics. We conclude that (1) the effect of sleep apnoea on arousal is no greater in the elderly compared to the young (2) despite similar levels of sleepiness, elderly apneoics perceive a reduced loss of QoL compared to younger patients.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherElsevier Ltden_US
dc.publisher.placeUnited Kingdomen_US
dc.publisher.urihttp://www.elsevier.com/locate/rmeden_AU
dc.relation.ispartofpagefrom1102en_US
dc.relation.ispartofpageto1108en_US
dc.relation.ispartofjournalRespiratory Medicineen_US
dc.relation.ispartofvolume97en_US
dc.subject.fieldofresearchcode320603en_US
dc.subject.fieldofresearchcode321007en_US
dc.titleSleep apnoea and daytime function in the elderly - what is the impact of arousal frequency?en_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.date.issued2003
gro.hasfulltextNo Full Text


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