Trifluoroethylsulfonate protected monosaccharides in glycosylation reactions
Author(s)
A. Karst, Nathalie
F. Islam, Tasneem
Y. Avci, Fikri
J. Linhardt, Robert
Griffith University Author(s)
Year published
2004
Metadata
Show full item recordAbstract
A variety of sulfo-protected monosaccharide donors and acceptors were investigated in glycosylation reactions. Trifluoroethylsulfonate (SO3TFE) group was compatible with a wide range of activation conditions commonly used with fluoride, imidate, and sulfide donors. In addition, the influence of a SO3TFE group, at the critical 2-position in glycosyl donor, on the stereoselectivity of the glycosylation reaction was studied.A variety of sulfo-protected monosaccharide donors and acceptors were investigated in glycosylation reactions. Trifluoroethylsulfonate (SO3TFE) group was compatible with a wide range of activation conditions commonly used with fluoride, imidate, and sulfide donors. In addition, the influence of a SO3TFE group, at the critical 2-position in glycosyl donor, on the stereoselectivity of the glycosylation reaction was studied.
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Journal Title
Tetrahedron Letters
Volume
45
Issue
34
Publisher URI
Subject
Medicinal and Biomolecular Chemistry
Organic Chemistry