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dc.contributor.authorBiroš, E.
dc.contributor.authorBodnár, J.
dc.contributor.authorBiroš, I.
dc.contributor.authorBirošová, E.
dc.contributor.authorMojžiš, J.
dc.contributor.authorHrivſák, M.
dc.contributor.authorKlimčáková, L.
dc.contributor.authorFindlay, Ian
dc.contributor.authorMiroššay, A.
dc.contributor.authorMiroššay, L.
dc.date.accessioned2017-05-03T16:59:24Z
dc.date.available2017-05-03T16:59:24Z
dc.date.issued2007
dc.date.modified2009-12-23T05:05:05Z
dc.identifier.issn00155632
dc.identifier.doi10.1007/BF02932100
dc.identifier.urihttp://hdl.handle.net/10072/27949
dc.description.abstractAn improved nucleic acid amplification test (NAAT) to detect Chlamydia trachomatis infections, based on PCR amplification within its cryptic plasmid (CT1/CT2 Test) was developed. DNA was extracted from urogenital swabs and a 594-bp long DNA fragment from the cryptic plasmid (pCT) was amplified. The sensitivity and specificity of the CT1/CT2 Test were determined to be 100 and 99 %, respectively, when directly compared with current amplification kit for sexually transmitted diseases (MPCR). Basic epidemiological data related to the patients attending gynecological and/or urological clinics are also provided. The overall prevalence rate in this group of patients suspected for C. trachomatis infection was determined to be about 95 per 1000 (88 and 107 per 1000 in females and males, respectively). It demonstrates that the CT1/CT2 Test is suitable for epidemiological screening and/or diagnostic practice.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer
dc.publisher.placeNew York, USA
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom437
dc.relation.ispartofpageto442
dc.relation.ispartofissue4
dc.relation.ispartofjournalFolia Microbiologica
dc.relation.ispartofvolume52
dc.rights.retentionY
dc.subject.fieldofresearchMicrobiology
dc.subject.fieldofresearchMedical Microbiology
dc.subject.fieldofresearchcode0605
dc.subject.fieldofresearchcode1108
dc.titleNucleic Acid Amplification Technique for Detection of Chlamydia trachomatis Infection from Clinical Urogenital Swabs
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2007
gro.hasfulltextNo Full Text
gro.griffith.authorFindlay, Ian


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