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  • Solid Medication Dosage Form Modification at the Bedside and in the Pharmacy of Queensland Hospitals

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    Author(s)
    Nissen, LM
    Haywood, A
    Steadman, KJ
    Griffith University Author(s)
    Haywood, Alison
    Year published
    2009
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    Abstract
    Background: Solid medication dosage forms are regularly modified to aid medication delivery to patients that are unable to swallow them. Aim: To identify medications that are commonly modified in Queensland hospitals at the bedside and in the pharmacy and to identify how these modifications are made. Method: A self-report survey was sent to 97 hospitals of varying sizes in metropolitan and rural areas across Queensland. Results: Most (n = 31; 79%) of the responding hospitals reported that medications were modified at the bedside. 73 different medications were modified at the bedside. Most of the tablets or capsules ...
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    Background: Solid medication dosage forms are regularly modified to aid medication delivery to patients that are unable to swallow them. Aim: To identify medications that are commonly modified in Queensland hospitals at the bedside and in the pharmacy and to identify how these modifications are made. Method: A self-report survey was sent to 97 hospitals of varying sizes in metropolitan and rural areas across Queensland. Results: Most (n = 31; 79%) of the responding hospitals reported that medications were modified at the bedside. 73 different medications were modified at the bedside. Most of the tablets or capsules had standard-release characteristics. 8 hospitals crushed modified-release dosage forms and 11 hospitals crushed medications with a narrow therapeutic index. At the bedside, 88% of medications were modified for adult use, mostly by crushing multiple tablets together (84% of hospitals) using a pestle and mortar (87%) and mixing into jam (72%) or water (64%). Only 7 hospitals reported modifications in the pharmacy (many small hospitals do not employ a pharmacist). 17 medications modified in the pharmacy were all modified for children because of the lack of commercial preparations.
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    Journal Title
    Journal of Pharmacy Practice and Research
    Volume
    39
    Issue
    2
    Publisher URI
    https://onlinelibrary.wiley.com/doi/10.1002/j.2055-2335.2009.tb00436.x
    DOI
    https://doi.org/10.1002/j.2055-2335.2009.tb00436.x
    Copyright Statement
    © 2009 Journal of Pharmacy Practice and Research. The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
    Subject
    Pharmacology and pharmaceutical sciences
    Clinical pharmacy and pharmacy practice
    Publication URI
    http://hdl.handle.net/10072/28572
    Collection
    • Journal articles

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