Telomerase activity: detection and clinical implications in human cancers
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Telomerase is an extremely important enzyme required for the immortalisation of tumour cells. Because the gene is activated in the vast majority of tumour tissues and remains unused in most somatic cells, it represents a marker with huge diagnostic, prognostic and treatment implications in cancer. This article summarises the basic structure and functions of telomerase and considers its clinical implications in colorectal and other cancers.
Clinical Laboratory International
© 2009 PanGlobal Media. Reproduced in accordance with the copyright policy of the publisher.Please refer to the journal link for access to the definitive, published version.