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dc.contributor.authorElsik, Christine G
dc.contributor.authorTellam, Ross L
dc.contributor.authorWorley, Kim C
dc.contributor.authorGibbs, Richard A
dc.contributor.authorAbatepaulo, Antonio RR
dc.contributor.authorAbbey, Colette A
dc.contributor.authorAdelson, David L
dc.contributor.authorAerts, Jan
dc.contributor.authorAhola, Virpi
dc.contributor.authorAlexander, Lee
dc.contributor.authorAlioto, Tyler
dc.contributor.authorAlmeida, Iassudara G
dc.contributor.authorAmadio, Ariel F
dc.contributor.authorAnatriello, Elen
dc.contributor.authorAntonarakis, Stylianos E
dc.contributor.authorAnzola, Juan M
dc.contributor.authorAstashyn, Alex
dc.contributor.authorBahadue, Suria M
dc.contributor.authorBaldwin, Cynthia L
dc.contributor.authorBarris, Wes
dc.contributor.authorBaxter, Rebecca
dc.contributor.authorBell, Stephanie Nicole
dc.contributor.authorBennett, Anna K
dc.contributor.authorBennett, Gary L
dc.contributor.authorBiase, Fernando H
dc.contributor.authorBoldt, Clayton R
dc.contributor.authorBradley, Daniel G
dc.contributor.authorBrinkman, Fiona SL
dc.contributor.authorBrinkmeyer-Langford, Candice L
dc.contributor.authorBrown, Wendy C
dc.contributor.authorBrownstein, Michael J
dc.contributor.authorBuhay, Christian
dc.contributor.authorCaetano, Alexandre R
dc.contributor.authorCamara, Francisco
dc.contributor.authorCarroll, Jeffrey A
dc.contributor.authorCarvalho, Wanessa A
dc.contributor.authorCasey, Theresa
dc.contributor.authorCervelatti, Elaine P
dc.contributor.authorChack, Joseph
dc.contributor.authorChacko, Elsa
dc.contributor.authorChandrabose, Mimi M
dc.contributor.authorChapin, Jennifer E
dc.contributor.authorChapple, Charles E
dc.contributor.authorChen, Hsiu-Chuan
dc.contributor.authorChen, Lin
dc.contributor.authorCheng, Ye
dc.contributor.authorCheng, Ze
dc.contributor.authorChilders, Christopher P
dc.contributor.authorChitko-McKown, Carol G
dc.contributor.authorChiu, Readman
dc.contributor.authorChoi, Jungwoo
dc.contributor.authorChrast, Jacqueline
dc.contributor.authorColley, Adam J
dc.contributor.authorConnelley, Tomothy
dc.contributor.authorCree, Andy
dc.contributor.authorCurry, Stacey
dc.contributor.authorDalrymple, Brian
dc.contributor.authorDiep Dao, Marvin
dc.contributor.authorDavis, Clay
dc.contributor.authorde Oliveira, Carlo JF
dc.contributor.authorde Miranda Santos, Isabel KF
dc.contributor.authorde Campos, Tatiana A
dc.contributor.authorDeobald, Heather
dc.contributor.authorDevinoy, Eve
dc.contributor.authorDickins, C Michael
dc.contributor.authorYan, Ding
dc.contributor.authorDinh, Huyen H
dc.contributor.authorDe Donato, Marcos
dc.contributor.authorDonohue, Kaitlin E
dc.contributor.authorDonthu, Ravikiran
dc.contributor.authorDovc, Peter
dc.contributor.authorDugan-Rocha, Shannon
dc.contributor.authorDurbin, K James
dc.contributor.authorEberlein, Annett
dc.contributor.authorEdgar, Robert C
dc.contributor.authorEgan, Amy
dc.contributor.authorEggen, Andre
dc.contributor.authorEichler, Evan E
dc.contributor.authorElhaik, Eran
dc.contributor.authorEllis, Shirley A
dc.contributor.authorElnitski, Laura
dc.contributor.authorErmolaeva, Olga
dc.contributor.authorEyras, Eduardo
dc.contributor.authorFitzsimmons, Carolyn J
dc.contributor.authorFowler, Gerald R
dc.contributor.authorFranzin, Alessandra M
dc.contributor.authorFritz, Krista
dc.contributor.authorGabisi, Ramatu Ayiesha
dc.contributor.authorGarcia, Gustavo R
dc.contributor.authorGarcia, Jose Fernando
dc.contributor.authorGenini, Sem
dc.contributor.authorGerlach, Daniel
dc.contributor.authorGerman, J Bruce
dc.contributor.authorGilbert, James GR
dc.contributor.authorGill, Clare A
dc.contributor.authorGladney, Cody J
dc.contributor.authorGlass, Elizabeth J
dc.contributor.authorGoodell, Jason
dc.contributor.authorGrant, Jason R
dc.contributor.authorGraur, Dan
dc.contributor.authorGreaser, Marion L
dc.contributor.authorGreen, Jonathan A
dc.contributor.authorGreen, Ronnie D
dc.contributor.authorGuan, Leluo
dc.contributor.authorGuigo, Roderic
dc.contributor.authorHadsell, Darryl L
dc.contributor.authorHagen, Darren E
dc.contributor.authorHakimov, Hatam A
dc.contributor.authorHalgren, Rob
dc.contributor.authorHamernik, Debora L
dc.contributor.authorHamilton, Cerissa
dc.contributor.authorHarhay, Gregory P
dc.contributor.authorHarrow, Jennifer L
dc.contributor.authorHart, Elizabeth A
dc.contributor.authorHastings, Nicola
dc.contributor.authorHavlak, Paul
dc.contributor.authorHenrichsen, Charlotte N
dc.contributor.authorHernandez, Judith
dc.contributor.authorHernandez, Marta
dc.contributor.authorHerzig, Carolyn TA
dc.contributor.authorHiendleder, Stefan G
dc.contributor.authorHines, Sandra
dc.contributor.authorHitchens, Matthew Edward
dc.contributor.authorHlavina, Wratko
dc.contributor.authorHobbs, Matthew
dc.contributor.authorHolder, Michael
dc.contributor.authorHolt, Robert A
dc.contributor.authorHu, Zhi-Liang
dc.contributor.authorHume, Jennifer
dc.contributor.authorIivanainen, Antti
dc.contributor.authorIngham, Aaron
dc.contributor.authorIso-Touru, Terhi
dc.contributor.authorJamis, Catherine
dc.contributor.authorJann, Oliver
dc.contributor.authorJensen, Kirsty
dc.contributor.authorJhangiani, Shalini N
dc.contributor.authorJiang, Huaiyang
dc.contributor.authorJohnson, Angela Jolivet
dc.contributor.authorJones, Steven JM
dc.contributor.authorJoshi, Vandita
dc.contributor.authorJunier, Thomas
dc.contributor.authorKapetis, Dimos
dc.contributor.authorKappes, Steve M
dc.contributor.authorKapustin, Yuri
dc.contributor.authorKeele, John W
dc.contributor.authorKent, Matthew P
dc.contributor.authorKerr, Tovah
dc.contributor.authorKhalil, Sari S
dc.contributor.authorKhatib, Hasan
dc.contributor.authorKiryutin, Boris
dc.contributor.authorKitts, Paul
dc.contributor.authorKokocinski, Felix
dc.contributor.authorKolbehdari, Davood
dc.contributor.authorKovar, Christie L
dc.contributor.authorKriventseva, Evgenia V
dc.contributor.authorKumar, Charu G
dc.contributor.authorKumar, Dinesh
dc.contributor.authorLahmers, Kevin K
dc.contributor.authorLandrum, Melissa
dc.contributor.authorLarkin, Denis M
dc.contributor.authorLau, Lilian PL
dc.contributor.authorLeach, Richard
dc.contributor.authorLee, Justin CM
dc.contributor.authorLee, Sandra
dc.contributor.authorLemay, Danielle G
dc.contributor.authorLewin, Harris A
dc.contributor.authorLewis, Lora R
dc.contributor.authorLi, Changxi
dc.contributor.authorLien, Sigbjorn
dc.contributor.authorLiu, George E
dc.contributor.authorLiu, Yih-shin
dc.contributor.authorLiu, Yue
dc.contributor.authorLogan, Krystin M
dc.contributor.authorLopez, John
dc.contributor.authorLozado, Ryan J
dc.contributor.authorLutzow, Ylva Strandberg
dc.contributor.authorLynn, David J
dc.contributor.authorMacNeil, Michael D
dc.contributor.authorMaglott, Donna
dc.contributor.authorMalinverni, Roberto
dc.contributor.authorMaqbool, Nauman J
dc.contributor.authorMarques, Elisa
dc.contributor.authorMarra, Marco A
dc.contributor.authorMartin, William F
dc.contributor.authorMartins, Natalia F
dc.contributor.authorMaruyama, Sandra R
dc.contributor.authorMatukumalli, Lakshmi K
dc.contributor.authorMazza, Raffaele
dc.contributor.authorMcEwan, John C
dc.contributor.authorMcKay, Stephanie D
dc.contributor.authorMcLean, Kim L
dc.contributor.authorMcWilliam, Sean
dc.contributor.authorMedrano, Juan F
dc.contributor.authorMemili, Erdogan
dc.contributor.authorMoen, Charles
dc.contributor.authorMolenaar, Adrian J
dc.contributor.authorMoore, Stephen S
dc.contributor.authorMoore, Richard
dc.contributor.authorMore, Daniela D
dc.contributor.authorMoreno, Barbara T
dc.contributor.authorMorgan, Margaret B
dc.contributor.authorMuntean, Carl T
dc.contributor.authorMuzny, Donna M
dc.contributor.authorNandakumar, Hari P
dc.contributor.authorNazareth, Lynne V
dc.contributor.authorNguyen, Ngoc Bich
dc.contributor.authorNicholas, Frank W
dc.contributor.authorNogueira, Marcelo FG
dc.contributor.authorOkwuonu, Geoffrey O
dc.contributor.authorOlsaker, Ingrid
dc.contributor.authorPant, Sameer D
dc.contributor.authorPanzitta, Francesca
dc.contributor.authorPastor, Rosemeire CP
dc.contributor.authorPatel, Bella Mayurkumar
dc.contributor.authorPayne, Gemma M
dc.contributor.authorPlass, Mireya
dc.contributor.authorPoli, Mario A
dc.contributor.authorPoslusny, Nathan
dc.contributor.authorPruitt, Kim
dc.contributor.authorPu, Ling-Ling
dc.contributor.authorQin, Xiang
dc.contributor.authorRachagani, Satyanarayana
dc.contributor.authorRaison, Joy M
dc.contributor.authorRanganathan, Shoba
dc.contributor.authorRatnakumar, Abhirami
dc.contributor.authorRazpet, Andrej
dc.contributor.authorReecy, James
dc.contributor.authorReese, Justin T
dc.contributor.authorRen, Yanru
dc.contributor.authorReymond, Alexandre
dc.contributor.authorRiggs, Penny K
dc.contributor.authorRijnkels, Monique
dc.contributor.authorRincon, Gonzalo
dc.contributor.authorRoberts, Andy
dc.contributor.authorRodriguez-Osorio, Nelida
dc.contributor.authorRodriguez-Zas, Sandra L
dc.contributor.authorRomero, Natasha E
dc.contributor.authorRosenwald, Anne
dc.contributor.authorRuiz, San Juana
dc.contributor.authorSabo, Aniko
dc.contributor.authorSalih, Hanni
dc.contributor.authorSando, Lillian
dc.contributor.authorSantibanez, Jireh
dc.contributor.authorSapojnikov, Victor
dc.contributor.authorSchein, Jacqueline E
dc.contributor.authorSchmutz, Sheila M
dc.contributor.authorSchnabel, Robert D
dc.contributor.authorSchook, Lawrence
dc.contributor.authorSearle, Stephen M
dc.contributor.authorSeo, Seongwon
dc.contributor.authorShen, Yufeng
dc.contributor.authorShen, Libing
dc.contributor.authorSherman, Laura
dc.contributor.authorSkow, Loren C
dc.contributor.authorSmith, Timothy
dc.contributor.authorSnelling, Warren M
dc.contributor.authorSodergren, Erica
dc.contributor.authorSolovyev, Victor
dc.contributor.authorSong, Henry
dc.contributor.authorSong, Jiuzhou
dc.contributor.authorSonstegard, Tad S
dc.contributor.authorSouthey, Bruce R
dc.contributor.authorSouvorov, Alexandre
dc.contributor.authorSpurlock, Diane
dc.contributor.authorSteffen, David
dc.contributor.authorStone, Roger T
dc.contributor.authorStothard, Paul
dc.contributor.authorSugimoto, Yoshikazu
dc.contributor.authorSweedler, Jonathan V
dc.contributor.authorTakasuga, Akiko
dc.contributor.authorTammen, Imke
dc.contributor.authorTaniguchi, Masaaki
dc.contributor.authorTaylor, Jeremy F
dc.contributor.authorTelugu, Bhanu Prakash VL
dc.contributor.authorUcla, Catherine
dc.contributor.authorUrbanski, Jennifer M
dc.contributor.authorUtsunomiya, Yuri T
dc.contributor.authorVan, Curtis P
dc.contributor.authorVattathil, Selina
dc.contributor.authorVerschoor, Chris P
dc.contributor.authorWaardenberg, Ashley J
dc.contributor.authorWalker, Angela
dc.contributor.authorWang, Zhiquan
dc.contributor.authorWard, Robert
dc.contributor.authorWarren, James T
dc.contributor.authorWaterman, Richard C
dc.contributor.authorWeikard, Rosemarie
dc.contributor.authorWeinstock, George M
dc.contributor.authorWelsh, Thomas H
dc.contributor.authorWheeler, David A
dc.contributor.authorWheeler, Thomas T
dc.contributor.authorWhite, Stephen N
dc.contributor.authorWhiteside, Matthew D
dc.contributor.authorWilczek-Boney, Katarzyna
dc.contributor.authorWilliams, John L
dc.contributor.authorWilliams, Rex Lee
dc.contributor.authorWilming, Laurens G
dc.contributor.authorWomack, James
dc.contributor.authorWright, Rita A
dc.contributor.authorWunderlich, Kris R
dc.contributor.authorWyss, Carine
dc.contributor.authorYang, Mary Q
dc.contributor.authorYang, Jianqi
dc.contributor.authorZdobnov, Evgeny M
dc.contributor.authorZhang, Jingkun
dc.contributor.authorZhao, Feng-Qi
dc.contributor.authorZhu, Bin
dc.date.accessioned2017-05-03T14:38:41Z
dc.date.available2017-05-03T14:38:41Z
dc.date.issued2009
dc.identifier.issn0036-8075
dc.identifier.doi10.1126/science.1169588
dc.identifier.urihttp://hdl.handle.net/10072/30032
dc.description.abstractTo understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a core set of 14,345 orthologs shared among seven mammalian species of which 1217 are absent or undetected in noneutherian (marsupial or monotreme) genomes. Cattle-specific evolutionary breakpoint regions in chromosomes have a higher density of segmental duplications, enrichment of repetitive elements, and species-specific variations in genes associated with lactation and immune responsiveness. Genes involved in metabolism are generally highly conserved, although five metabolic genes are deleted or extensively diverged from their human orthologs. The cattle genome sequence thus provides a resource for understanding mammalian evolution and accelerating livestock genetic improvement for milk and meat production.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherAmerican Association for the Advancement of Science
dc.publisher.placeUnited States
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom522
dc.relation.ispartofpageto528
dc.relation.ispartofissue5926
dc.relation.ispartofjournalScience
dc.relation.ispartofvolume324
dc.rights.retentionY
dc.subject.fieldofresearchGenome Structure and Regulation
dc.subject.fieldofresearchcode060407
dc.titleThe Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2014-10-10T01:55:59Z
gro.hasfulltextNo Full Text
gro.griffith.authorWaardenberg, Ashley


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