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dc.contributor.authorKiefel, Miltonen_US
dc.contributor.authorvon Itzstein, Marken_US
dc.contributor.authorI. Angus, Donalden_US
dc.date.accessioned2017-04-24T10:38:33Z
dc.date.available2017-04-24T10:38:33Z
dc.date.issued2000en_US
dc.date.modified2007-03-13T21:56:38Z
dc.identifier.issn0968-0896en_US
dc.identifier.urihttp://hdl.handle.net/10072/3016
dc.description.abstractThe intimate involvement of carbohydrate-protein interactions in a number of important biological processes has prompted several research efforts towards developing new methods of investigating these glycobiological interactions. Biotinylated oligosaccharides are emerging as a new and powerful tool in this area of research, primarily due to their high affinity towards streptavidin and their ease of immobilization on matrices. Here we describe a novel synthetic approach towards biotinylated saccharides which incorporate a UV absorbing group into the final compounds. The synthetic strategy described is applicable to a variety of saccharides, with examples of biotinylated mono-, di-, and trisaccharides being prepared with overall high efficiency.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherPergamonen_US
dc.publisher.placeUKen_US
dc.publisher.urihttp://www.elsevier.com/wps/find/journaldescription.cws_home/129/description#descriptionen_AU
dc.relation.ispartofpagefrom2709en_US
dc.relation.ispartofpageto2718en_US
dc.relation.ispartofjournalBioorganic & Medicinal Chemistryen_US
dc.relation.ispartofvolume8en_US
dc.subject.fieldofresearchcode250301en_US
dc.titleThe synthesis of biotinylated carbohydrates as probes for carbohydrate-recognizing proteinsen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.facultyOffice of the Snr Dep Vice Chancellor, Institute for Glycomicsen_US
gro.rights.copyrightCopyright 2000 Elsevier : Reproduced in accordance with the copyright policy of the publisher : This journal is available online - use hypertext links.en_AU
gro.date.issued2000
gro.hasfulltextNo Full Text


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