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dc.contributor.authorCraske, Michelle G
dc.contributor.authorWaters, Allison M
dc.contributor.authorNazarian, Maria
dc.contributor.authorMineka, Susan
dc.contributor.authorZinbarg, Richard E
dc.contributor.authorGriffith, James W
dc.contributor.authorNaliboff, Bruce
dc.contributor.authorOrnitz, Edward M
dc.date.accessioned2017-05-03T14:37:41Z
dc.date.available2017-05-03T14:37:41Z
dc.date.issued2009
dc.date.modified2010-06-25T07:02:00Z
dc.identifier.issn0006-3223
dc.identifier.doi10.1016/j.biopsych.2008.07.020
dc.identifier.urihttp://hdl.handle.net/10072/30710
dc.description.abstractBackground This study evaluated the relationship between neuroticism (N), a probable risk factor for emotional disorders, and modulation of startle reflexes (SRs). Methods One hundred thirty-two adolescents with varying levels of N but without anxiety or depressive disorders were evaluated in contextual cue and explicit threat cue paradigms. Results Within the explicit threat cue paradigm, N potentiated SRs more in conditions that were intermediately associated with threat of an aversive biceps contraction than conditions that were the furthest from and conditions that were the closest to the same threat. Also, N potentiated SRs across the entire experiment, regardless of experimental conditions, in male and not in female subjects. Conclusions These results suggest that adolescents with high levels of N show greater sensitivity to contexts intermediately associated with threat. Results are discussed in comparison with other studies of groups at risk for anxiety and depressive disorders.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.publisher.placeNetherlands
dc.publisher.urihttp://www.sciencedirect.com/science/journal/00063223
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom220
dc.relation.ispartofpageto226
dc.relation.ispartofissue3
dc.relation.ispartofjournalBiological Psychiatry
dc.relation.ispartofvolume65
dc.rights.retentionY
dc.subject.fieldofresearchBiological sciences
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchPsychology
dc.subject.fieldofresearchOther psychology not elsewhere classified
dc.subject.fieldofresearchcode31
dc.subject.fieldofresearchcode32
dc.subject.fieldofresearchcode52
dc.subject.fieldofresearchcode529999
dc.titleDoes neuroticism in adolescents moderate contextual and explicit threat cue modulation of the startle reflex?
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2009
gro.hasfulltextNo Full Text
gro.griffith.authorWaters, Allison M.


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