Genetic legacy of the mutiny on the Bounty: Use of the Norfolk Island population for CVD and migraine gene mapping
Author(s)
Griffiths, Lyn
Bellis, Claire
Lea, Rodney
Cox, Hannah
Macgregor, Stuart
Visscher, Peter
Quinlan, Sharon
Dyer, T.
Blangero, J.
Griffith University Author(s)
Year published
2009
Metadata
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Summary Our research is aimed at identifying the genes that play a role in CVD and migraine and the Norfolk population may be of significant use in these endeavours. Norfolk Islanders are primarily descended from 18th Century English (Bounty) sailors and Polynesian women. DNA samples from ~70% of the Islands' adult population have been prepared, heritability and power estimates determined, LD investigated and a recent full microsatellite genome scan undertaken.Summary Our research is aimed at identifying the genes that play a role in CVD and migraine and the Norfolk population may be of significant use in these endeavours. Norfolk Islanders are primarily descended from 18th Century English (Bounty) sailors and Polynesian women. DNA samples from ~70% of the Islands' adult population have been prepared, heritability and power estimates determined, LD investigated and a recent full microsatellite genome scan undertaken.
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Conference Title
4th International Meeting on Genetics of Complex Diseases and Isolated Populations Programme
Publisher URI
Subject
Population, Ecological and Evolutionary Genetics