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  • Current status and the future of buccal drug delivery systems

    Author(s)
    Pather, S Indiran
    J. Rathbone, Michael
    Senel, Sevda
    Griffith University Author(s)
    Rathbone, Michael
    Year published
    2008
    Metadata
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    Abstract
    Background : The delivery of drugs through the buccal mucosa has received a great deal of attention over the last two decades, and yet there are not many buccal delivery products available on the market. Objective : This review outlines the advantages and disadvantages of buccal drug delivery, provides a historical perspective and discusses representative developmental and marketed drugs. Methods : The structure of the oral mucosa is briefly described to preface a description of the pathways for drug absorption and a critical discussion of permeation experiments. A brief historical perspective followed by a description of ...
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    Background : The delivery of drugs through the buccal mucosa has received a great deal of attention over the last two decades, and yet there are not many buccal delivery products available on the market. Objective : This review outlines the advantages and disadvantages of buccal drug delivery, provides a historical perspective and discusses representative developmental and marketed drugs. Methods : The structure of the oral mucosa is briefly described to preface a description of the pathways for drug absorption and a critical discussion of permeation experiments. A brief historical perspective followed by a description of some of the currently marketed products provides a picture of where we are today. An indication is given of likely progress in this area and of the attributes of a successful business entity of the future. Conclusion : The authors provide an assessment of the future potential of buccal and sublingual drugs.
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    Journal Title
    Expert Opinion on Drug delivery
    Volume
    5
    Issue
    5
    Publisher URI
    http://informahealthcare.com/doi/abs/10.1517/17425247.5.5.531
    Subject
    Pharmacology and Pharmaceutical Sciences not elsewhere classified
    Pharmacology and Pharmaceutical Sciences
    Publication URI
    http://hdl.handle.net/10072/32111
    Collection
    • Journal articles

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