dc.contributor.author | Amarasinghe, Hemantha K | |
dc.contributor.author | Usgodaarachchi, Udaya S | |
dc.contributor.author | Johnson, Newell W | |
dc.contributor.author | Lalloo, Ratilal | |
dc.contributor.author | Warnakulasuriya, Saman | |
dc.date.accessioned | 2017-05-03T15:32:18Z | |
dc.date.available | 2017-05-03T15:32:18Z | |
dc.date.issued | 2010 | |
dc.identifier.issn | 1368-8375 | |
dc.identifier.doi | 10.1016/j.oraloncology.2010.01.017 | |
dc.identifier.uri | http://hdl.handle.net/10072/32247 | |
dc.description.abstract | We investigated the prevalence of, and risk factors for, oral potentially malignant disorders (OPMDs) in rural Sri Lanka. A cross-sectional community-based study was conducted by interview and oral examination of 1029 subjects aged over 30 years. A community-based nested case-control study then took those with OPMDs as 'cases', ''controls" being those with no oral abnormalities at time of initial screening. The prevalence of OPMD was 11.3% (95% CI: 9.4-13.2), after weighting for place of residence and gender. Risk factors were betel-quid (BQ) chewing daily [OR = 10.6 (95% CI: 3.6-31.0)] and alcohol drinking daily or weekly [OR = 3.55 (1.6-8.0)]. A significant dose-response relationship existed for BQ chewing. Smoking did not emerge when adjusted for covariates. A synergistic effect of chewing and alcohol consumption existed. The attributable risk (AR) of daily BQ chewing was 90.6%, the population AR 84%. This study demonstrates high prevalence of OPMD, betel-quid chewing with or without tobacco being the major risk factor. | |
dc.description.peerreviewed | Yes | |
dc.description.publicationstatus | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Elsevier | |
dc.publisher.place | United Kingdom | |
dc.relation.ispartofstudentpublication | N | |
dc.relation.ispartofpagefrom | 297 | |
dc.relation.ispartofpageto | 301 | |
dc.relation.ispartofissue | 4 | |
dc.relation.ispartofjournal | Oral Oncology | |
dc.relation.ispartofvolume | 46 | |
dc.rights.retention | Y | |
dc.subject.fieldofresearch | Dentistry | |
dc.subject.fieldofresearch | Oral medicine and pathology | |
dc.subject.fieldofresearch | Dentistry not elsewhere classified | |
dc.subject.fieldofresearch | Oncology and carcinogenesis | |
dc.subject.fieldofresearchcode | 3203 | |
dc.subject.fieldofresearchcode | 320307 | |
dc.subject.fieldofresearchcode | 320399 | |
dc.subject.fieldofresearchcode | 3211 | |
dc.title | Betel-quid chewing with or without tobacco is a major risk factor for oral potentially malignant disorders in Sri Lanka: A case-control study | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.date.issued | 2015-05-15T04:40:44Z | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Johnson, Newell W. | |