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dc.contributor.authorAmarasinghe, Hemantha K
dc.contributor.authorUsgodaarachchi, Udaya S
dc.contributor.authorJohnson, Newell W
dc.contributor.authorLalloo, Ratilal
dc.contributor.authorWarnakulasuriya, Saman
dc.date.accessioned2017-05-03T15:32:18Z
dc.date.available2017-05-03T15:32:18Z
dc.date.issued2010
dc.identifier.issn1368-8375
dc.identifier.doi10.1016/j.oraloncology.2010.01.017
dc.identifier.urihttp://hdl.handle.net/10072/32247
dc.description.abstractWe investigated the prevalence of, and risk factors for, oral potentially malignant disorders (OPMDs) in rural Sri Lanka. A cross-sectional community-based study was conducted by interview and oral examination of 1029 subjects aged over 30 years. A community-based nested case-control study then took those with OPMDs as 'cases', ''controls" being those with no oral abnormalities at time of initial screening. The prevalence of OPMD was 11.3% (95% CI: 9.4-13.2), after weighting for place of residence and gender. Risk factors were betel-quid (BQ) chewing daily [OR = 10.6 (95% CI: 3.6-31.0)] and alcohol drinking daily or weekly [OR = 3.55 (1.6-8.0)]. A significant dose-response relationship existed for BQ chewing. Smoking did not emerge when adjusted for covariates. A synergistic effect of chewing and alcohol consumption existed. The attributable risk (AR) of daily BQ chewing was 90.6%, the population AR 84%. This study demonstrates high prevalence of OPMD, betel-quid chewing with or without tobacco being the major risk factor.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.publisher.placeUnited Kingdom
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom297
dc.relation.ispartofpageto301
dc.relation.ispartofissue4
dc.relation.ispartofjournalOral Oncology
dc.relation.ispartofvolume46
dc.rights.retentionY
dc.subject.fieldofresearchDentistry
dc.subject.fieldofresearchOral medicine and pathology
dc.subject.fieldofresearchDentistry not elsewhere classified
dc.subject.fieldofresearchOncology and carcinogenesis
dc.subject.fieldofresearchcode3203
dc.subject.fieldofresearchcode320307
dc.subject.fieldofresearchcode320399
dc.subject.fieldofresearchcode3211
dc.titleBetel-quid chewing with or without tobacco is a major risk factor for oral potentially malignant disorders in Sri Lanka: A case-control study
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2015-05-15T04:40:44Z
gro.hasfulltextNo Full Text
gro.griffith.authorJohnson, Newell W.


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