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dc.contributor.authorMaguire, David
dc.contributor.authorLintell, Nicholas
dc.contributor.authorMcCabe, Michael
dc.contributor.authorGriffiths, Lyn
dc.date.accessioned2017-05-03T11:46:27Z
dc.date.available2017-05-03T11:46:27Z
dc.date.issued2005
dc.date.modified2010-08-09T07:16:26Z
dc.identifier.issn00652598
dc.identifier.doi10.1007/0-387-26206-7_49
dc.identifier.urihttp://hdl.handle.net/10072/33008
dc.description.abstractIn recent years, with the development of techniques in modern molecular biology, it has become possible to study the genetic basis of carcinogenesis down to the level of DNA sequence. Major advances have been made in our understanding of the genes involved in cell cycle control and descriptions of mutations in those genes. These developments have led to the definition of the role of specific oncogenes and tumour suppressor genes in several cancers, including, for example, colon cancers and some forms of breast cancer. Work reported from our laboratory has led to the identification of a number of candidate genes involved in the development of non-melanotic skin cancers. In this chapter, we attempt to further explain the observed (phenomic) alterations in metabolic pathways associated with oxygen consumption with the changes at the genetic level.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer New York LLC
dc.publisher.placeUnited States
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom375
dc.relation.ispartofpageto380
dc.relation.ispartofjournalAdvances in Experimental Medicine and Biology
dc.relation.ispartofvolume566
dc.rights.retentionY
dc.subject.fieldofresearchMedical and Health Sciences not elsewhere classified
dc.subject.fieldofresearchMedical and Health Sciences
dc.subject.fieldofresearchcode119999
dc.subject.fieldofresearchcode11
dc.titleFocussing on Genomic and Phenomic Correlations in Respiration of Non-Melanotic Skin Cancers
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2005
gro.hasfulltextNo Full Text
gro.griffith.authorMaguire, David J.
gro.griffith.authorMcCabe, Michael
gro.griffith.authorGriffiths, Lyn
gro.griffith.authorLintell, Nicholas


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