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dc.contributor.authorDavies, Murrayen_US
dc.contributor.authorHall, Matthewen_US
dc.contributor.authorJ. Berners-Price, Susanen_US
dc.contributor.authorHambley, Trevoren_US
dc.date.accessioned2017-04-24T13:16:10Z
dc.date.available2017-04-24T13:16:10Z
dc.date.issued2008en_US
dc.date.modified2010-11-04T07:06:44Z
dc.identifier.issn00201669en_US
dc.identifier.urihttp://hdl.handle.net/10072/33040
dc.description.abstractThe aquation and hydrolysis of a series of platinum(IV) complexes of the general form cis, trans, cis-[PtCl 2(X) 2( (15)NH 3) 2] (X = Cl (-), O 2CCH 3 (-), OH (-)) have been followed by [ (1)H, (15)N] Heteronuclear Single Quantum Coherence NMR spectroscopy. Negligible aquation (<5%) is observed for the complexes where X = O 2CCH 3 (-) or OH (-) over 3-4 weeks. Aquation of cis-[PtCl 4( (15)NH 3) 2] ( 1) is observed, and the rate of aquation increases with increasing pH and upon the addition of 0.01 mol equiv of the platinum(II) complex cis-[PtCl 2( (15)NH 3) 2] (cisplatin). The first aquated species formed from cis-[PtCl 4(NH 3) 2] has one of the axial chloro groups (relative to the equatorial NH 3 ligands) replaced by an aqua/hydroxo ligand. The second observed substitution occurs in an equatorial position. Peaks that are consistent with five of the eight possible aquation species were observed in the NMR spectra.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherAmerican Chemical Societyen_US
dc.publisher.placeUnited Statesen_US
dc.publisher.urihttp://pubs.acs.org/journal/inocajen_AU
dc.relation.ispartofstudentpublicationNen_AU
dc.relation.ispartofpagefrom7673en_US
dc.relation.ispartofpageto7680en_US
dc.relation.ispartofissue17en_US
dc.relation.ispartofjournalInorganic Chemistryen_US
dc.relation.ispartofvolume47en_US
dc.rights.retentionYen_AU
dc.subject.fieldofresearchBioinorganic Chemistryen_US
dc.subject.fieldofresearchcode030201en_US
dc.title[1H, 15N] heteronuclear single quantum coherence NMR study of the mechanism of aquation of platinum(IV) ammine complexes.en_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.rights.copyrightCopyright 2008 American Chemical Society. Self-archiving of the author-manuscript version is not yet supported by this publisher. Please refer to the journal link for access to the definitive, published version or contact the authors for more information.en_AU
gro.date.issued2008
gro.hasfulltextNo Full Text


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