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dc.contributor.authorCraig, Philipen_US
dc.contributor.authorEllis, Magdaen_US
dc.contributor.authorGray, Darrenen_US
dc.contributor.authorMcManus, Donen_US
dc.contributor.authorYang, Yu Rongen_US
dc.contributor.authorYang, Shu Kunen_US
dc.date.accessioned2017-04-04T18:33:59Z
dc.date.available2017-04-04T18:33:59Z
dc.date.issued2009en_US
dc.date.modified2010-10-19T07:00:29Z
dc.identifier.issn1756-3305en_US
dc.identifier.doi10.1186/1756-3305-2-53en_AU
dc.identifier.urihttp://hdl.handle.net/10072/33068
dc.description.abstractAbstract During analysis of retrospective community survey data, we identified two patients from Xiji County, south Ningxia Hui Autonomous Region with simultaneous echinococcosis and tuberculosis (TB), representing the first such reports for China. As the echinococcosis chronicity increased, the immune profile in both subjects changed from a Th1 to Th2 response, as shown by a TB skin test, originally positive, becoming negative. Such an elevated Th2 immune profile, with subsequent suppression of the Th1 immune response, is a common feature of chronic helminth infections. Given the difficulties in definitive diagnosis, and the potential increased susceptibility for TB infection in patients with advanced echinococcosis, we suggest that combined TB/echinococcosis surveys be undertaken in this area in the future. This would allow early diagnosis of both TB and echinococcosis cases with better prognosis for effective and sustainable treatment outcomes, ultimately reducing associated morbidity and mortality, and also the overall financial costs to the individual and the public health care system in this under developed part of China.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.format.extent772991 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherBioMed Centralen_US
dc.publisher.placeUnited Kingdomen_US
dc.relation.ispartofstudentpublicationNen_AU
dc.relation.ispartofpagefrom1en_US
dc.relation.ispartofpageto5en_US
dc.relation.ispartofjournalParasites & Vectorsen_US
dc.relation.ispartofvolume2en_US
dc.rights.retentionYen_AU
dc.subject.fieldofresearchMedical Parasitologyen_US
dc.subject.fieldofresearchcode110803en_US
dc.titleHuman cases of simultaneous echinococcosis and tuberculosis - significance and extent in Chinaen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.facultyGriffith Health, School of Public Healthen_US
gro.rights.copyrightCopyright 2009 Gray et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_AU
gro.date.issued2009
gro.hasfulltextFull Text


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