Bioactivity of Syzygium jambos methanolic extracts: Antibacterial activity and toxicity
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Methanol extracts from S. jambos leaves were tested for antimicrobial activity and toxicity. S. jambos leaf extract inhibited the growth of 4 of the 14 bacteria tested (29%). Both Gram-positive and Gram-negative bacterial growth were inhibited by S. jambos leaf extract although Gram-positive bacteria appeared more susceptible. 2 of the 10 Gram-negative bacteria (20%) and 2 of the 4 Gram-positive bacteria (50%) tested had their growth inhibited by the extract. The leaf extract also proved to be toxic in the Artemia franciscana bioassay with a 48 h LC50 of 387.9 ᠳ8.8 姯ml, making it slightly more toxic than Mevinphos (505.3 ᠳ7.7 姯ml) and approximately 5 fold less toxic than potassium dichromate (80.4 ᠴ.3姯ml). Whilst potassium dichromate's LC50 remained constant across the 72 hour test period (24h LC50 86.3 ᠵ.1; 72h LC50 77.9 ᠴ.9), the extract and Mevinphos LC50 values decreased by 72 hours (87.0 ᠱ1.3 姯ml and 103.9 ᠱ2.8 姯ml respectively), indicating their similar level of toxicity in the assay.
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Biological Sciences not elsewhere classified