Isolation and structure determination of two new hydrophobic microcystins from Microcystis sp. (CAWBG11)

Puddick, Jonathan; Prinsep, Michele R.; Wood, Susanna A.; Cary, S. Craig; Hamilton, David P.; Wilkins, Alistair L.

doi:10.1016/j.phytol.2013.07.011

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Year published

2013

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Abstract

Two new hydrophobic microcystins, microcystin-FA (1) and microcystin-WA (2), were isolated from the cyanobacterium Microcystis sp. (CAWBG11). The structures were deduced using one- and two-dimensional nuclear magnetic resonance spectroscopy and tandem mass spectrometry. The absolute stereochemistry of the amino acid residues in 1 and 2 was determined using the Advanced Marfey's method.Two new hydrophobic microcystins, microcystin-FA (1) and microcystin-WA (2), were isolated from the cyanobacterium Microcystis sp. (CAWBG11). The structures were deduced using one- and two-dimensional nuclear magnetic resonance spectroscopy and tandem mass spectrometry. The absolute stereochemistry of the amino acid residues in 1 and 2 was determined using the Advanced Marfey's method.
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Journal Title

Phytochemistry Letters

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Issue

DOI

https://doi.org/10.1016/j.phytol.2013.07.011

Subject

Medicinal and Biomolecular Chemistry not elsewhere classified

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http://hdl.handle.net/10072/337281

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Journal articles