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dc.contributor.authorCross, Troyen_US
dc.contributor.authorSabapathy, Surendranen_US
dc.contributor.authorSchneider, Donalden_US
dc.contributor.authorHaseler, Lukeen_US
dc.contributor.editorDavid Patersonen_US
dc.date.accessioned2017-04-24T10:25:21Z
dc.date.available2017-04-24T10:25:21Z
dc.date.issued2010en_US
dc.date.modified2011-06-07T06:57:17Z
dc.identifier.issn0958-0670en_US
dc.identifier.doi10.1113/expphysiol.2009.048975en_AU
dc.identifier.urihttp://hdl.handle.net/10072/34056
dc.description.abstractThe contribution of respiratory muscle O2 uptake ((.)V(O2RM)) to the development of the slow component of O2 uptake kinetics ((.)V(O2SC)) is unclear. The aim of the present study was to examine the impact of respiratory muscle unloading (via breathing, a He-O2 mixture) on the amplitude of (.)V(O2SC) during exercise performed below (B-RCT) and above the respiratory compensation threshold (A-RCT). We hypothesized that breathing He-O2 would reduce the amplitude of the (.)V(O2SC) by a greater amount during exercise performed A-RCT than B-RCT. Eight healthy male recreational cyclists performed constant load cycling in four sets of conditions: (1) B-RCT breathing normal air; (2) B-RCT breathing He-O2; (3) A-RCT breathing normal air; and (4) A-RCT breathing He-O2. Breathing He-O2 did not significantly attenuate the (.)V(O2SC) during exercise performed B-RCT (-3+/-14%, P >0.05). However, breathing He-O2 significantly reduced the (.)V(O2SC) during exercise A-RCT(-45+/-6%, P <0.05). The attenuated (.)V(O2SC) while breathing He-O2 is likely to reflect a decreased (.)V(O2RM). Minute ventilation was not +/-different between normal air and He-O2 breathing trials either B-RCT or A-RCT. However, operating lung volume was significantly lower when breathing He-O2 during exercise performed A-RCT (-12+/-3%, P <0.05). These findings suggest that (.)V(O2RM) comprises a greater proportion of the (.)V(O2SC) when exercise is performed A-RCT compared with B-RCT. Therefore, the impact of breathing He-O2 was more pronounced during exercise A-RCT. Furthermore, changes in operating lung volume and the work of breathing appear to play an important role in the development of the (.)V(O2SC).en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherWiley-Blackwell Publishingen_US
dc.publisher.placeUnited Kingdomen_US
dc.relation.ispartofstudentpublicationNen_AU
dc.relation.ispartofpagefrom172en_US
dc.relation.ispartofpageto183en_US
dc.relation.ispartofissue1en_US
dc.relation.ispartofjournalExperimental Physiologyen_US
dc.relation.ispartofvolume95en_US
dc.rights.retentionNen_AU
dc.subject.fieldofresearchExercise Physiologyen_US
dc.subject.fieldofresearchcode110602en_US
dc.titleBreathing HeO2 attenuates the amplitude of the slow component of O2 uptake kinetics during exercise performed above the respiratory compensation thresholden_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.date.issued2010
gro.hasfulltextNo Full Text


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