Few-Layer Graphdiyne Nanosheets Applied for Multiplexed Real-Time DNA Detection
Author(s)
Parvin, Nargish
Jin, Quan
Wei, Yanze
Yu, Ranbo
Zheng, Bing
Huang, Ling
Zhang, Ying
Wang, Lianhui
Zhang, Hua
Gao, Mingyuan
Zhao, Huijun
Hu, Wenping
Li, Yuliang
Wang, Dan
Griffith University Author(s)
Year published
2017
Metadata
Show full item recordAbstract
Despite recent progress in 2D nanomaterials-based biosensing, it remains challenging to achieve sensitive and high selective detection. This study develops few-layer graphdiyne (GD) nanosheets (NSs) that are used as novel sensing platforms for a variety of fluorophores real-time detection of DNA with low background and high signal-to-noise ratio, which show a distinguished fluorescence quenching ability and different affinities toward single-stranded DNA and double-stranded DNA. Importantly, for the first time, a few-layer GD NSs-based multiplexed DNA sensor is developed.Despite recent progress in 2D nanomaterials-based biosensing, it remains challenging to achieve sensitive and high selective detection. This study develops few-layer graphdiyne (GD) nanosheets (NSs) that are used as novel sensing platforms for a variety of fluorophores real-time detection of DNA with low background and high signal-to-noise ratio, which show a distinguished fluorescence quenching ability and different affinities toward single-stranded DNA and double-stranded DNA. Importantly, for the first time, a few-layer GD NSs-based multiplexed DNA sensor is developed.
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Journal Title
Advanced Materials
Volume
29
Issue
18
Subject
Physical sciences
Chemical sciences
Engineering
Materials engineering not elsewhere classified