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  • Few-Layer Graphdiyne Nanosheets Applied for Multiplexed Real-Time DNA Detection

    Author(s)
    Parvin, Nargish
    Jin, Quan
    Wei, Yanze
    Yu, Ranbo
    Zheng, Bing
    Huang, Ling
    Zhang, Ying
    Wang, Lianhui
    Zhang, Hua
    Gao, Mingyuan
    Zhao, Huijun
    Hu, Wenping
    Li, Yuliang
    Wang, Dan
    Griffith University Author(s)
    Zhao, Huijun
    Year published
    2017
    Metadata
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    Abstract
    Despite recent progress in 2D nanomaterials-based biosensing, it remains challenging to achieve sensitive and high selective detection. This study develops few-layer graphdiyne (GD) nanosheets (NSs) that are used as novel sensing platforms for a variety of fluorophores real-time detection of DNA with low background and high signal-to-noise ratio, which show a distinguished fluorescence quenching ability and different affinities toward single-stranded DNA and double-stranded DNA. Importantly, for the first time, a few-layer GD NSs-based multiplexed DNA sensor is developed.Despite recent progress in 2D nanomaterials-based biosensing, it remains challenging to achieve sensitive and high selective detection. This study develops few-layer graphdiyne (GD) nanosheets (NSs) that are used as novel sensing platforms for a variety of fluorophores real-time detection of DNA with low background and high signal-to-noise ratio, which show a distinguished fluorescence quenching ability and different affinities toward single-stranded DNA and double-stranded DNA. Importantly, for the first time, a few-layer GD NSs-based multiplexed DNA sensor is developed.
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    Journal Title
    Advanced Materials
    Volume
    29
    Issue
    18
    DOI
    https://doi.org/10.1002/adma.201606755
    Subject
    Physical sciences
    Chemical sciences
    Engineering
    Materials engineering not elsewhere classified
    Publication URI
    http://hdl.handle.net/10072/340759
    Collection
    • Journal articles

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